| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| apt | gmk | BDP_1173 | BDP_0741 | Adenine phosphoribosyltransferase (APRT); Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Gmk Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.962 |
| apt | guaA | BDP_1173 | BDP_1005 | Adenine phosphoribosyltransferase (APRT); Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | GMP synthase glutamine amidotransferase; Catalyzes the synthesis of GMP from XMP. | 0.981 |
| apt | guaB | BDP_1173 | BDP_0621 | Adenine phosphoribosyltransferase (APRT); Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | guaB Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.469 |
| apt | hprT | BDP_1173 | BDP_0548 | Adenine phosphoribosyltransferase (APRT); Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | hprT Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.965 |
| apt | purA | BDP_1173 | BDP_0089 | Adenine phosphoribosyltransferase (APRT); Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Adenylsuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.639 |
| apt | purH | BDP_1173 | BDP_1169 | Adenine phosphoribosyltransferase (APRT); Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase. | 0.974 |
| ftsH | hprT | BDP_0549 | BDP_0548 | ftsH Cell division protein; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | hprT Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.953 |
| ftsH | tilS | BDP_0549 | BDP_0547 | ftsH Cell division protein; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | Putative lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. | 0.904 |
| gmk | apt | BDP_0741 | BDP_1173 | Gmk Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Adenine phosphoribosyltransferase (APRT); Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.962 |
| gmk | guaA | BDP_0741 | BDP_1005 | Gmk Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | GMP synthase glutamine amidotransferase; Catalyzes the synthesis of GMP from XMP. | 0.976 |
| gmk | guaB | BDP_0741 | BDP_0621 | Gmk Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | guaB Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.457 |
| gmk | hprT | BDP_0741 | BDP_0548 | Gmk Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | hprT Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.960 |
| guaA | apt | BDP_1005 | BDP_1173 | GMP synthase glutamine amidotransferase; Catalyzes the synthesis of GMP from XMP. | Adenine phosphoribosyltransferase (APRT); Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.981 |
| guaA | gmk | BDP_1005 | BDP_0741 | GMP synthase glutamine amidotransferase; Catalyzes the synthesis of GMP from XMP. | Gmk Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.976 |
| guaA | guaB | BDP_1005 | BDP_0621 | GMP synthase glutamine amidotransferase; Catalyzes the synthesis of GMP from XMP. | guaB Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.999 |
| guaA | guaC | BDP_1005 | BDP_1206 | GMP synthase glutamine amidotransferase; Catalyzes the synthesis of GMP from XMP. | guaC GMP reductase,fadD1 Long-chain-fatty-acid--CoA ligase. | 0.999 |
| guaA | hprT | BDP_1005 | BDP_0548 | GMP synthase glutamine amidotransferase; Catalyzes the synthesis of GMP from XMP. | hprT Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.970 |
| guaA | magZ | BDP_1005 | BDP_1344 | GMP synthase glutamine amidotransferase; Catalyzes the synthesis of GMP from XMP. | MazG-like conserved hypothetical protein. | 0.903 |
| guaA | purA | BDP_1005 | BDP_0089 | GMP synthase glutamine amidotransferase; Catalyzes the synthesis of GMP from XMP. | Adenylsuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.923 |
| guaA | purH | BDP_1005 | BDP_1169 | GMP synthase glutamine amidotransferase; Catalyzes the synthesis of GMP from XMP. | Bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase. | 0.789 |