| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BDP_0643 | ftsE | BDP_0643 | BDP_0641 | CHAP domain containing protein. | ftsE Cell division ATP-binding protein ftsE; Part of the ABC transporter FtsEX involved in cellular division. | 0.701 |
| BDP_0643 | ftsQ | BDP_0643 | BDP_1539 | CHAP domain containing protein. | ftsQ Cell division protein ftsQ. | 0.543 |
| BDP_0643 | ftsX | BDP_0643 | BDP_0642 | CHAP domain containing protein. | ftsX Cell division protein ftsX; Part of the ABC transporter FtsEX involved in cellular division; Belongs to the ABC-4 integral membrane protein family. FtsX subfamily. | 0.763 |
| BDP_0643 | prfB | BDP_0643 | BDP_0639 | CHAP domain containing protein. | prfB Bacterial Peptide Chain Release Factor 2 (RF-2); Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. | 0.693 |
| BDP_0643 | smpB | BDP_0643 | BDP_0644 | CHAP domain containing protein. | smpB SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switch [...] | 0.693 |
| der | ffh | BDP_1165 | BDP_0314 | Bifunctional cytidylate kinase/GTP-binding protein; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the cytidylate kinase family. Type 1 subfamily. | Ffh Signal recognition particle, subunit FFH/SRP54; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | 0.847 |
| der | ftsE | BDP_1165 | BDP_0641 | Bifunctional cytidylate kinase/GTP-binding protein; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the cytidylate kinase family. Type 1 subfamily. | ftsE Cell division ATP-binding protein ftsE; Part of the ABC transporter FtsEX involved in cellular division. | 0.512 |
| der | ftsY | BDP_1165 | BDP_0187 | Bifunctional cytidylate kinase/GTP-binding protein; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the cytidylate kinase family. Type 1 subfamily. | FtsY signal recognition particle; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | 0.714 |
| der | smpB | BDP_1165 | BDP_0644 | Bifunctional cytidylate kinase/GTP-binding protein; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the cytidylate kinase family. Type 1 subfamily. | smpB SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switch [...] | 0.507 |
| ffh | der | BDP_0314 | BDP_1165 | Ffh Signal recognition particle, subunit FFH/SRP54; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | Bifunctional cytidylate kinase/GTP-binding protein; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the cytidylate kinase family. Type 1 subfamily. | 0.847 |
| ffh | ftsE | BDP_0314 | BDP_0641 | Ffh Signal recognition particle, subunit FFH/SRP54; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | ftsE Cell division ATP-binding protein ftsE; Part of the ABC transporter FtsEX involved in cellular division. | 0.628 |
| ffh | ftsY | BDP_0314 | BDP_0187 | Ffh Signal recognition particle, subunit FFH/SRP54; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | FtsY signal recognition particle; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | 0.999 |
| ffh | smpB | BDP_0314 | BDP_0644 | Ffh Signal recognition particle, subunit FFH/SRP54; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | smpB SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switch [...] | 0.692 |
| fstW | ftsE | BDP_1543 | BDP_0641 | fstW Cell division protein ftsW; Belongs to the SEDS family. | ftsE Cell division ATP-binding protein ftsE; Part of the ABC transporter FtsEX involved in cellular division. | 0.639 |
| fstW | ftsQ | BDP_1543 | BDP_1539 | fstW Cell division protein ftsW; Belongs to the SEDS family. | ftsQ Cell division protein ftsQ. | 0.952 |
| fstW | ftsX | BDP_1543 | BDP_0642 | fstW Cell division protein ftsW; Belongs to the SEDS family. | ftsX Cell division protein ftsX; Part of the ABC transporter FtsEX involved in cellular division; Belongs to the ABC-4 integral membrane protein family. FtsX subfamily. | 0.443 |
| fstW | ftsZ-2 | BDP_1543 | BDP_1592 | fstW Cell division protein ftsW; Belongs to the SEDS family. | Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | 0.824 |
| ftsE | BDP_0643 | BDP_0641 | BDP_0643 | ftsE Cell division ATP-binding protein ftsE; Part of the ABC transporter FtsEX involved in cellular division. | CHAP domain containing protein. | 0.701 |
| ftsE | der | BDP_0641 | BDP_1165 | ftsE Cell division ATP-binding protein ftsE; Part of the ABC transporter FtsEX involved in cellular division. | Bifunctional cytidylate kinase/GTP-binding protein; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the cytidylate kinase family. Type 1 subfamily. | 0.512 |
| ftsE | ffh | BDP_0641 | BDP_0314 | ftsE Cell division ATP-binding protein ftsE; Part of the ABC transporter FtsEX involved in cellular division. | Ffh Signal recognition particle, subunit FFH/SRP54; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | 0.628 |