purM protein (Bifidobacterium dentium) - STRING interaction network

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purM

purM Phosphoribosylformylglycinamidine cyclo-ligase. (344 aa)

Predicted Functional Partners:

purD

0.999

purL

0.999

purF

0.998

purK

0.994

BDP_0726

0.992

purB

0.988

purE

0.972

purH

0.971

thrB

0.880

guaB

0.825

Your Current Organism:

Bifidobacterium dentium

NCBI taxonomy Id: 401473
Other names: B. dentium Bd1, Bifidobacterium dentium Bd1, Bifidobacterium dentium str. Bd1, Bifidobacterium dentium strain Bd1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BDP_0726	guaB	BDP_0726	BDP_0621	Phosphoribosylaminoimidazole-succinocarboxamide synthase.	guaB Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	0.722
BDP_0726	purB	BDP_0726	BDP_0760	Phosphoribosylaminoimidazole-succinocarboxamide synthase.	purB Adenylosuccinate lyase.	0.999
BDP_0726	purD	BDP_0726	BDP_0718	Phosphoribosylaminoimidazole-succinocarboxamide synthase.	purD Phosphoribosylamine--glycine ligase; Belongs to the GARS family.	0.990
BDP_0726	purE	BDP_0726	BDP_0714	Phosphoribosylaminoimidazole-succinocarboxamide synthase.	purE Phosphoribosylaminoimidazole carboxylase carboxyltransferase subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).	0.992
BDP_0726	purF	BDP_0726	BDP_0720	Phosphoribosylaminoimidazole-succinocarboxamide synthase.	purF Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.	0.962
BDP_0726	purH	BDP_0726	BDP_1169	Phosphoribosylaminoimidazole-succinocarboxamide synthase.	Bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase.	0.979
BDP_0726	purK	BDP_0726	BDP_0715	Phosphoribosylaminoimidazole-succinocarboxamide synthase.	purK Phosphoribosylaminoimidazole carboxylase NCAIR mutase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).	0.990
BDP_0726	purL	BDP_0726	BDP_0725	Phosphoribosylaminoimidazole-succinocarboxamide synthase.	purL Phosphoribosylformylglycinamidine synthase.	0.998
BDP_0726	purM	BDP_0726	BDP_0719	Phosphoribosylaminoimidazole-succinocarboxamide synthase.	purM Phosphoribosylformylglycinamidine cyclo-ligase.	0.992
guaB	BDP_0726	BDP_0621	BDP_0726	guaB Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	Phosphoribosylaminoimidazole-succinocarboxamide synthase.	0.722
guaB	purB	BDP_0621	BDP_0760	guaB Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	purB Adenylosuccinate lyase.	0.813
guaB	purD	BDP_0621	BDP_0718	guaB Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	purD Phosphoribosylamine--glycine ligase; Belongs to the GARS family.	0.690
guaB	purE	BDP_0621	BDP_0714	guaB Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	purE Phosphoribosylaminoimidazole carboxylase carboxyltransferase subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).	0.708
guaB	purF	BDP_0621	BDP_0720	guaB Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	purF Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.	0.816
guaB	purH	BDP_0621	BDP_1169	guaB Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	Bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase.	0.992
guaB	purK	BDP_0621	BDP_0715	guaB Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	purK Phosphoribosylaminoimidazole carboxylase NCAIR mutase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).	0.881
guaB	purL	BDP_0621	BDP_0725	guaB Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	purL Phosphoribosylformylglycinamidine synthase.	0.884
guaB	purM	BDP_0621	BDP_0719	guaB Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	purM Phosphoribosylformylglycinamidine cyclo-ligase.	0.825
purB	BDP_0726	BDP_0760	BDP_0726	purB Adenylosuccinate lyase.	Phosphoribosylaminoimidazole-succinocarboxamide synthase.	0.999
purB	guaB	BDP_0760	BDP_0621	purB Adenylosuccinate lyase.	guaB Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	0.813