purB protein (Bifidobacterium dentium) - STRING interaction network

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Score

purB

purB Adenylosuccinate lyase. (484 aa)

Predicted Functional Partners:

BDP_0726

0.999

purL

0.995

purA

0.993

purK

0.992

purH

0.992

purE

0.991

purF

0.991

purM

0.988

purD

0.968

apt

0.966

Your Current Organism:

Bifidobacterium dentium

NCBI taxonomy Id: 401473
Other names: B. dentium Bd1, Bifidobacterium dentium Bd1, Bifidobacterium dentium str. Bd1, Bifidobacterium dentium strain Bd1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BDP_0726	purA	BDP_0726	BDP_0089	Phosphoribosylaminoimidazole-succinocarboxamide synthase.	Adenylsuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.	0.959
BDP_0726	purB	BDP_0726	BDP_0760	Phosphoribosylaminoimidazole-succinocarboxamide synthase.	purB Adenylosuccinate lyase.	0.999
BDP_0726	purD	BDP_0726	BDP_0718	Phosphoribosylaminoimidazole-succinocarboxamide synthase.	purD Phosphoribosylamine--glycine ligase; Belongs to the GARS family.	0.990
BDP_0726	purE	BDP_0726	BDP_0714	Phosphoribosylaminoimidazole-succinocarboxamide synthase.	purE Phosphoribosylaminoimidazole carboxylase carboxyltransferase subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).	0.992
BDP_0726	purF	BDP_0726	BDP_0720	Phosphoribosylaminoimidazole-succinocarboxamide synthase.	purF Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.	0.962
BDP_0726	purH	BDP_0726	BDP_1169	Phosphoribosylaminoimidazole-succinocarboxamide synthase.	Bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase.	0.979
BDP_0726	purK	BDP_0726	BDP_0715	Phosphoribosylaminoimidazole-succinocarboxamide synthase.	purK Phosphoribosylaminoimidazole carboxylase NCAIR mutase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).	0.990
BDP_0726	purL	BDP_0726	BDP_0725	Phosphoribosylaminoimidazole-succinocarboxamide synthase.	purL Phosphoribosylformylglycinamidine synthase.	0.998
BDP_0726	purM	BDP_0726	BDP_0719	Phosphoribosylaminoimidazole-succinocarboxamide synthase.	purM Phosphoribosylformylglycinamidine cyclo-ligase.	0.992
apt	purA	BDP_1173	BDP_0089	Adenine phosphoribosyltransferase (APRT); Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	Adenylsuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.	0.647
apt	purB	BDP_1173	BDP_0760	Adenine phosphoribosyltransferase (APRT); Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	purB Adenylosuccinate lyase.	0.966
apt	purE	BDP_1173	BDP_0714	Adenine phosphoribosyltransferase (APRT); Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	purE Phosphoribosylaminoimidazole carboxylase carboxyltransferase subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).	0.405
apt	purF	BDP_1173	BDP_0720	Adenine phosphoribosyltransferase (APRT); Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	purF Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.	0.477
apt	purH	BDP_1173	BDP_1169	Adenine phosphoribosyltransferase (APRT); Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	Bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase.	0.978
apt	purL	BDP_1173	BDP_0725	Adenine phosphoribosyltransferase (APRT); Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	purL Phosphoribosylformylglycinamidine synthase.	0.704
purA	BDP_0726	BDP_0089	BDP_0726	Adenylsuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.	Phosphoribosylaminoimidazole-succinocarboxamide synthase.	0.959
purA	apt	BDP_0089	BDP_1173	Adenylsuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.	Adenine phosphoribosyltransferase (APRT); Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	0.647
purA	purB	BDP_0089	BDP_0760	Adenylsuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.	purB Adenylosuccinate lyase.	0.993
purA	purD	BDP_0089	BDP_0718	Adenylsuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.	purD Phosphoribosylamine--glycine ligase; Belongs to the GARS family.	0.716
purA	purE	BDP_0089	BDP_0714	Adenylsuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.	purE Phosphoribosylaminoimidazole carboxylase carboxyltransferase subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).	0.950