| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BDP_0037 | trpA | BDP_0037 | BDP_1191 | Para-aminobenzoate synthase glutamine amidotransferase component II. | TrpA Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.949 |
| BDP_0037 | trpBC | BDP_0037 | BDP_1192 | Para-aminobenzoate synthase glutamine amidotransferase component II. | Indole-3-glycerol phosphate synthase; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine; Belongs to the TrpC family. | 0.992 |
| BDP_0037 | trpD | BDP_0037 | BDP_1417 | Para-aminobenzoate synthase glutamine amidotransferase component II. | trpD Anthranilate phosphoribosyltransferase. | 0.997 |
| BDP_0037 | trpE | BDP_0037 | BDP_1193 | Para-aminobenzoate synthase glutamine amidotransferase component II. | trpE Anthranilate synthase component I. | 0.999 |
| cysK | glyA | BDP_0670 | BDP_1264 | cysK cysteine synthase. | Glycine/serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.950 |
| cysK | sdaA | BDP_0670 | BDP_0875 | cysK cysteine synthase. | L-serine dehydratase. | 0.929 |
| cysK | serB1 | BDP_0670 | BDP_0750 | cysK cysteine synthase. | serB1 Phosphoserine phosphatase. | 0.931 |
| cysK | tdcB | BDP_0670 | BDP_2220 | cysK cysteine synthase. | TdcB Threonine dehydratase. | 0.924 |
| cysK | trpA | BDP_0670 | BDP_1191 | cysK cysteine synthase. | TrpA Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.932 |
| cysK | trpBC | BDP_0670 | BDP_1192 | cysK cysteine synthase. | Indole-3-glycerol phosphate synthase; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine; Belongs to the TrpC family. | 0.910 |
| glyA | cysK | BDP_1264 | BDP_0670 | Glycine/serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | cysK cysteine synthase. | 0.950 |
| glyA | sdaA | BDP_1264 | BDP_0875 | Glycine/serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | L-serine dehydratase. | 0.969 |
| glyA | serB1 | BDP_1264 | BDP_0750 | Glycine/serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | serB1 Phosphoserine phosphatase. | 0.936 |
| glyA | tdcB | BDP_1264 | BDP_2220 | Glycine/serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | TdcB Threonine dehydratase. | 0.941 |
| glyA | trpA | BDP_1264 | BDP_1191 | Glycine/serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | TrpA Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.925 |
| glyA | trpBC | BDP_1264 | BDP_1192 | Glycine/serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Indole-3-glycerol phosphate synthase; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine; Belongs to the TrpC family. | 0.929 |
| lgt | trpA | BDP_1190 | BDP_1191 | Lgt Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. | TrpA Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.987 |
| lgt | trpBC | BDP_1190 | BDP_1192 | Lgt Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. | Indole-3-glycerol phosphate synthase; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine; Belongs to the TrpC family. | 0.978 |
| lgt | trpE | BDP_1190 | BDP_1193 | Lgt Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. | trpE Anthranilate synthase component I. | 0.638 |
| sdaA | cysK | BDP_0875 | BDP_0670 | L-serine dehydratase. | cysK cysteine synthase. | 0.929 |
