nrdD protein (Bifidobacterium dentium) - STRING interaction network

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nrdD

nrdD Anaerobic ribonucleoside-triphosphate reductase. (799 aa)

Predicted Functional Partners:

nrdG

0.996

pyrG

0.962

dut

0.920

dcd

0.906

BDP_1927

0.904

relA1

0.903

dgt

0.900

relA2

0.900

cyaB

0.900

folE

0.801

Your Current Organism:

Bifidobacterium dentium

NCBI taxonomy Id: 401473
Other names: B. dentium Bd1, Bifidobacterium dentium Bd1, Bifidobacterium dentium str. Bd1, Bifidobacterium dentium strain Bd1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BDP_1927	nrdD	BDP_1927	BDP_1694	Maf-like protein; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.	nrdD Anaerobic ribonucleoside-triphosphate reductase.	0.904
BDP_1927	pyrG	BDP_1927	BDP_1030	Maf-like protein; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.	CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.	0.913
cyaB	folE	BDP_1935	BDP_0550	Adenylate cyclase.	GTP cyclohydrolase I.	0.800
cyaB	nrdD	BDP_1935	BDP_1694	Adenylate cyclase.	nrdD Anaerobic ribonucleoside-triphosphate reductase.	0.900
cyaB	relA1	BDP_1935	BDP_1398	Adenylate cyclase.	relA1 GTP pyrophosphokinase/Guanosine 3',5'-bis(Diphosphate)3'-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.	0.900
cyaB	relA2	BDP_1935	BDP_1431	Adenylate cyclase.	relA2 GTP pyrophosphokinase.	0.900
dcd	dut	BDP_2233	BDP_1399	Dcd Deoxycytidine triphosphate deaminase; Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.	Dut Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.	0.936
dcd	nrdD	BDP_2233	BDP_1694	Dcd Deoxycytidine triphosphate deaminase; Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.	nrdD Anaerobic ribonucleoside-triphosphate reductase.	0.906
dgt	nrdD	BDP_0679	BDP_1694	Dgt Deoxyguanosinetriphosphate triphosphohydrolase.	nrdD Anaerobic ribonucleoside-triphosphate reductase.	0.900
dut	dcd	BDP_1399	BDP_2233	Dut Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.	Dcd Deoxycytidine triphosphate deaminase; Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.	0.936
dut	nrdD	BDP_1399	BDP_1694	Dut Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.	nrdD Anaerobic ribonucleoside-triphosphate reductase.	0.920
dut	relA1	BDP_1399	BDP_1398	Dut Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.	relA1 GTP pyrophosphokinase/Guanosine 3',5'-bis(Diphosphate)3'-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.	0.684
folE	cyaB	BDP_0550	BDP_1935	GTP cyclohydrolase I.	Adenylate cyclase.	0.800
folE	nrdD	BDP_0550	BDP_1694	GTP cyclohydrolase I.	nrdD Anaerobic ribonucleoside-triphosphate reductase.	0.801
folE	nrdG	BDP_0550	BDP_1693	GTP cyclohydrolase I.	nrdG Anaerobic ribonucleoside-triphosphate reductase activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.	0.413
folE	relA1	BDP_0550	BDP_1398	GTP cyclohydrolase I.	relA1 GTP pyrophosphokinase/Guanosine 3',5'-bis(Diphosphate)3'-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.	0.800
folE	relA2	BDP_0550	BDP_1431	GTP cyclohydrolase I.	relA2 GTP pyrophosphokinase.	0.800
nrdD	BDP_1927	BDP_1694	BDP_1927	nrdD Anaerobic ribonucleoside-triphosphate reductase.	Maf-like protein; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.	0.904
nrdD	cyaB	BDP_1694	BDP_1935	nrdD Anaerobic ribonucleoside-triphosphate reductase.	Adenylate cyclase.	0.900
nrdD	dcd	BDP_1694	BDP_2233	nrdD Anaerobic ribonucleoside-triphosphate reductase.	Dcd Deoxycytidine triphosphate deaminase; Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.	0.906