node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
A0A0D9YDJ1 | A0A0D9YQ35 | A0A0D9YDJ1 | A0A0D9YQ35 | Uncharacterized protein. | Elp3 domain-containing protein. | 0.888 |
A0A0D9YDJ1 | A0A0D9YTQ0 | A0A0D9YDJ1 | A0A0D9YTQ0 | Uncharacterized protein. | Molybdopterin synthase sulfur carrier subunit; Acts as a sulfur carrier required for molybdopterin biosynthesis. Component of the molybdopterin synthase complex that catalyzes the conversion of precursor Z into molybdopterin by mediating the incorporation of 2 sulfur atoms into precursor Z to generate a dithiolene group. In the complex, serves as sulfur donor by being thiocarboxylated (-COSH) at its C-terminus by MOCS3. After interaction with MOCS2B, the sulfur is then transferred to precursor Z to form molybdopterin. | 0.958 |
A0A0D9YDJ1 | A0A0D9ZLQ0 | A0A0D9YDJ1 | A0A0D9ZLQ0 | Uncharacterized protein. | MoaC domain-containing protein. | 0.888 |
A0A0D9YDJ1 | A0A0D9ZRY2 | A0A0D9YDJ1 | A0A0D9ZRY2 | Uncharacterized protein. | Molybdopterin molybdenumtransferase; Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released. | 0.988 |
A0A0D9YDJ1 | A0A0E0ANH6 | A0A0D9YDJ1 | A0A0E0ANH6 | Uncharacterized protein. | NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. | 0.466 |
A0A0D9YDJ1 | A0A0E0BT55 | A0A0D9YDJ1 | A0A0E0BT55 | Uncharacterized protein. | Elp3 domain-containing protein. | 0.888 |
A0A0D9YDJ1 | MOCS3-2 | A0A0D9YDJ1 | A0A0D9YZT7 | Uncharacterized protein. | Adenylyltransferase and sulfurtransferase MOCS3; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers URM1 and MOCS2A. Its N-terminus first activates URM1 and MOCS2A as acyl- adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 and MOCS2A to form thiocarboxylation (- COSH) of their C-terminus. The reaction probably involves hydrogen sulfide [...] | 0.885 |
A0A0D9YM61 | A0A0D9YQ35 | A0A0D9YM61 | A0A0D9YQ35 | Molybdopterin synthase catalytic subunit; Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin. Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group. | Elp3 domain-containing protein. | 0.963 |
A0A0D9YM61 | A0A0D9YTQ0 | A0A0D9YM61 | A0A0D9YTQ0 | Molybdopterin synthase catalytic subunit; Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin. Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group. | Molybdopterin synthase sulfur carrier subunit; Acts as a sulfur carrier required for molybdopterin biosynthesis. Component of the molybdopterin synthase complex that catalyzes the conversion of precursor Z into molybdopterin by mediating the incorporation of 2 sulfur atoms into precursor Z to generate a dithiolene group. In the complex, serves as sulfur donor by being thiocarboxylated (-COSH) at its C-terminus by MOCS3. After interaction with MOCS2B, the sulfur is then transferred to precursor Z to form molybdopterin. | 0.985 |
A0A0D9YM61 | A0A0D9ZLQ0 | A0A0D9YM61 | A0A0D9ZLQ0 | Molybdopterin synthase catalytic subunit; Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin. Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group. | MoaC domain-containing protein. | 0.985 |
A0A0D9YM61 | A0A0D9ZRY2 | A0A0D9YM61 | A0A0D9ZRY2 | Molybdopterin synthase catalytic subunit; Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin. Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group. | Molybdopterin molybdenumtransferase; Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released. | 0.996 |
A0A0D9YM61 | A0A0E0AD23 | A0A0D9YM61 | A0A0E0AD23 | Molybdopterin synthase catalytic subunit; Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin. Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group. | Molybdenum cofactor sulfurase; Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form. | 0.503 |
A0A0D9YM61 | A0A0E0ANH6 | A0A0D9YM61 | A0A0E0ANH6 | Molybdopterin synthase catalytic subunit; Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin. Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group. | NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. | 0.466 |
A0A0D9YM61 | A0A0E0BT55 | A0A0D9YM61 | A0A0E0BT55 | Molybdopterin synthase catalytic subunit; Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin. Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group. | Elp3 domain-containing protein. | 0.963 |
A0A0D9YM61 | MOCS3-2 | A0A0D9YM61 | A0A0D9YZT7 | Molybdopterin synthase catalytic subunit; Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin. Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group. | Adenylyltransferase and sulfurtransferase MOCS3; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers URM1 and MOCS2A. Its N-terminus first activates URM1 and MOCS2A as acyl- adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 and MOCS2A to form thiocarboxylation (- COSH) of their C-terminus. The reaction probably involves hydrogen sulfide [...] | 0.977 |
A0A0D9YQ35 | A0A0D9YDJ1 | A0A0D9YQ35 | A0A0D9YDJ1 | Elp3 domain-containing protein. | Uncharacterized protein. | 0.888 |
A0A0D9YQ35 | A0A0D9YM61 | A0A0D9YQ35 | A0A0D9YM61 | Elp3 domain-containing protein. | Molybdopterin synthase catalytic subunit; Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin. Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group. | 0.963 |
A0A0D9YQ35 | A0A0D9YTQ0 | A0A0D9YQ35 | A0A0D9YTQ0 | Elp3 domain-containing protein. | Molybdopterin synthase sulfur carrier subunit; Acts as a sulfur carrier required for molybdopterin biosynthesis. Component of the molybdopterin synthase complex that catalyzes the conversion of precursor Z into molybdopterin by mediating the incorporation of 2 sulfur atoms into precursor Z to generate a dithiolene group. In the complex, serves as sulfur donor by being thiocarboxylated (-COSH) at its C-terminus by MOCS3. After interaction with MOCS2B, the sulfur is then transferred to precursor Z to form molybdopterin. | 0.945 |
A0A0D9YQ35 | A0A0D9ZLQ0 | A0A0D9YQ35 | A0A0D9ZLQ0 | Elp3 domain-containing protein. | MoaC domain-containing protein. | 0.966 |
A0A0D9YQ35 | A0A0D9ZRY2 | A0A0D9YQ35 | A0A0D9ZRY2 | Elp3 domain-containing protein. | Molybdopterin molybdenumtransferase; Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released. | 0.937 |