STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A0E0B043DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (977 aa)    
Predicted Functional Partners:
A0A0E0APD2
ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.
  
 0.958
A0A0D9Y432
DUF1767 domain-containing protein.
    
 0.941
A0A0D9Z0R3
ERCC4 domain-containing protein.
    
 0.939
A0A0E0BG20
Uncharacterized protein.
   
 0.922
A0A0D9YJZ4
ERCC4 domain-containing protein.
    
 0.891
A0A0E0B4W4
Toprim domain-containing protein.
     
0.871
A0A0D9ZKZ0
Uncharacterized protein.
  
 0.864
A0A0D9YZ88
Uncharacterized protein.
  
 0.808
A0A0D9ZMD3
Uncharacterized protein.
  
 0.808
A0A0D9ZUB2
Uncharacterized protein.
  
 0.808
Your Current Organism:
Oryza glumipatula
NCBI taxonomy Id: 40148
Other names: O. glumipatula, Oryza glumaepatula, Oryza glumipatula Steud.
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.