node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KTR03888.1 | KTR04320.1 | NS365_17140 | NS365_15710 | 2-hydroxy-acid oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Isocitrate lyase; Catalyzes the reversible formation of glyoxylate and succinate from isocitrate; glyoxylate bypass pathway; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.706 |
KTR03888.1 | KTR05976.1 | NS365_17140 | NS365_09285 | 2-hydroxy-acid oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Malic enzyme; NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.755 |
KTR03888.1 | KTR06630.1 | NS365_17140 | NS365_07095 | 2-hydroxy-acid oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Malic enzyme; NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.755 |
KTR03888.1 | glcB | NS365_17140 | NS365_16410 | 2-hydroxy-acid oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Malate synthase; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. | 0.862 |
KTR03888.1 | gltA | NS365_17140 | NS365_00825 | 2-hydroxy-acid oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the citrate synthase family. | 0.554 |
KTR03888.1 | mdh | NS365_17140 | NS365_11515 | 2-hydroxy-acid oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. | 0.511 |
KTR04319.1 | KTR04320.1 | NS365_15705 | NS365_15710 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Isocitrate lyase; Catalyzes the reversible formation of glyoxylate and succinate from isocitrate; glyoxylate bypass pathway; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.743 |
KTR04319.1 | KTR04321.1 | NS365_15705 | NS365_15715 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cro/Cl family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.705 |
KTR04320.1 | KTR03888.1 | NS365_15710 | NS365_17140 | Isocitrate lyase; Catalyzes the reversible formation of glyoxylate and succinate from isocitrate; glyoxylate bypass pathway; Derived by automated computational analysis using gene prediction method: Protein Homology. | 2-hydroxy-acid oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.706 |
KTR04320.1 | KTR04319.1 | NS365_15710 | NS365_15705 | Isocitrate lyase; Catalyzes the reversible formation of glyoxylate and succinate from isocitrate; glyoxylate bypass pathway; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.743 |
KTR04320.1 | KTR04321.1 | NS365_15710 | NS365_15715 | Isocitrate lyase; Catalyzes the reversible formation of glyoxylate and succinate from isocitrate; glyoxylate bypass pathway; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cro/Cl family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.776 |
KTR04320.1 | KTR05976.1 | NS365_15710 | NS365_09285 | Isocitrate lyase; Catalyzes the reversible formation of glyoxylate and succinate from isocitrate; glyoxylate bypass pathway; Derived by automated computational analysis using gene prediction method: Protein Homology. | Malic enzyme; NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.956 |
KTR04320.1 | KTR06630.1 | NS365_15710 | NS365_07095 | Isocitrate lyase; Catalyzes the reversible formation of glyoxylate and succinate from isocitrate; glyoxylate bypass pathway; Derived by automated computational analysis using gene prediction method: Protein Homology. | Malic enzyme; NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.956 |
KTR04320.1 | KTR06687.1 | NS365_15710 | NS365_05965 | Isocitrate lyase; Catalyzes the reversible formation of glyoxylate and succinate from isocitrate; glyoxylate bypass pathway; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HpcH/HpaI aldolase family. | 0.710 |
KTR04320.1 | KTR06750.1 | NS365_15710 | NS365_06420 | Isocitrate lyase; Catalyzes the reversible formation of glyoxylate and succinate from isocitrate; glyoxylate bypass pathway; Derived by automated computational analysis using gene prediction method: Protein Homology. | Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | 0.881 |
KTR04320.1 | glcB | NS365_15710 | NS365_16410 | Isocitrate lyase; Catalyzes the reversible formation of glyoxylate and succinate from isocitrate; glyoxylate bypass pathway; Derived by automated computational analysis using gene prediction method: Protein Homology. | Malate synthase; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. | 0.993 |
KTR04320.1 | gltA | NS365_15710 | NS365_00825 | Isocitrate lyase; Catalyzes the reversible formation of glyoxylate and succinate from isocitrate; glyoxylate bypass pathway; Derived by automated computational analysis using gene prediction method: Protein Homology. | Type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the citrate synthase family. | 0.790 |
KTR04320.1 | mdh | NS365_15710 | NS365_11515 | Isocitrate lyase; Catalyzes the reversible formation of glyoxylate and succinate from isocitrate; glyoxylate bypass pathway; Derived by automated computational analysis using gene prediction method: Protein Homology. | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. | 0.721 |
KTR04321.1 | KTR04319.1 | NS365_15715 | NS365_15705 | Cro/Cl family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.705 |
KTR04321.1 | KTR04320.1 | NS365_15715 | NS365_15710 | Cro/Cl family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | Isocitrate lyase; Catalyzes the reversible formation of glyoxylate and succinate from isocitrate; glyoxylate bypass pathway; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.776 |