STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KTR03694.1Thioredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. (329 aa)    
Predicted Functional Partners:
KTR02654.1
Thioredoxin reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.968
KTR06624.1
Glutathione reductase; Maintains high levels of reduced glutathione.
  
 
 0.942
hslU
ATP-dependent protease; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
   
 
 0.904
hslV
Hypothetical protein; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
  
  
 0.891
grpE
Molecular chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP [...]
  
  
 0.875
htpG
Heat shock protein 90; Molecular chaperone. Has ATPase activity.
  
 
 0.851
fusA
Elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
    
 
 0.836
KTR06019.1
Arsenate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
  
 
 0.835
KTR03731.1
DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.800
KTR02703.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.795
Your Current Organism:
Aureimonas ureilytica
NCBI taxonomy Id: 401562
Other names: A. ureilytica, Aurantimonas ureilytica, Aurantimonas ureilytica Weon et al. 2007, Aureimonas ureilytica (Weon et al. 2007) Rathsack et al. 2011, CIP 109815, DSM 18598, KACC 11607, NBRC 106430, strain 5715S-12
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