STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A0N7LAW8Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (196 aa)    
Predicted Functional Partners:
A0A0P1BI33
Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.
   
 0.977
A0A0P1BD75
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
  
 0.973
A0A0P1BR09
Gmp synthase.
  
 
 0.961
A0A0P1BSD4
Amp deaminase.
    
 0.952
A0A0N7LAI2
Nucleoside diphosphate kinase.
  
 0.947
A0A0P1BPP8
Adenine phosphoribosyltransferase.
  
 0.947
A0A0P1BCD8
Gtp cyclohydrolase i.
  
 
 0.943
A0A0N7LB65
Aicarft impchase bienzyme.
     
 0.938
A0A0P1BQM5
Pyruvate kinase; Belongs to the pyruvate kinase family.
    
 0.938
A0A0P1BFG7
Nucleoside phosphatase; Belongs to the GDA1/CD39 NTPase family.
    
 0.928
Your Current Organism:
Ceraceosorus bombacis
NCBI taxonomy Id: 401625
Other names: ATCC 22867, C. bombacis, Dicellomyces bombacis
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