node1 | node2 | node1 annotation | node2 annotation | score |
A0A0N7L996 | A0A0P1B808 | Thymidylate synthase. | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | 0.836 |
A0A0N7L996 | A0A0P1B8P3 | Thymidylate synthase. | Dihydrofolate reductase; Belongs to the dihydrofolate reductase family. | 0.996 |
A0A0N7L996 | A0A0P1BBK9 | Thymidylate synthase. | Anthranilate synthase component. | 0.421 |
A0A0N7L996 | A0A0P1BCD8 | Thymidylate synthase. | Gtp cyclohydrolase i. | 0.614 |
A0A0N7L996 | A0A0P1BEG7 | Thymidylate synthase. | Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | 0.576 |
A0A0N7L996 | A0A0P1BEY3 | Thymidylate synthase. | Related to multifunctional folic acid synthesis protein. | 0.886 |
A0A0N7L996 | A0A0P1BFS6 | Thymidylate synthase. | Fthfs-domain-containing protein. | 0.935 |
A0A0N7L996 | A0A0P1BIZ7 | Thymidylate synthase. | Folylpolyglutamate synthase. | 0.835 |
A0A0N7L996 | A0A0P1BLS4 | Thymidylate synthase. | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. | 0.943 |
A0A0N7L996 | A0A0P1BN62 | Thymidylate synthase. | Para-aminobenzoate (PABA) synthase ABZ1. | 0.421 |
A0A0P1B808 | A0A0N7L996 | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | Thymidylate synthase. | 0.836 |
A0A0P1B808 | A0A0P1B8P3 | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | Dihydrofolate reductase; Belongs to the dihydrofolate reductase family. | 0.954 |
A0A0P1B808 | A0A0P1BBK9 | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | Anthranilate synthase component. | 0.577 |
A0A0P1B808 | A0A0P1BCD8 | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | Gtp cyclohydrolase i. | 0.697 |
A0A0P1B808 | A0A0P1BEG7 | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | 0.723 |
A0A0P1B808 | A0A0P1BEY3 | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | Related to multifunctional folic acid synthesis protein. | 0.988 |
A0A0P1B808 | A0A0P1BFS6 | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | Fthfs-domain-containing protein. | 0.869 |
A0A0P1B808 | A0A0P1BIZ7 | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | Folylpolyglutamate synthase. | 0.874 |
A0A0P1B808 | A0A0P1BLS4 | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. | 0.882 |
A0A0P1B808 | A0A0P1BN62 | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | Para-aminobenzoate (PABA) synthase ABZ1. | 0.629 |