STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIRAS1DIRAS family GTPase 1. (197 aa)    
Predicted Functional Partners:
PIK3CB
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta.
    
 0.945
ITSN2
Intersectin 2.
    
 0.929
ITSN1
Intersectin 1.
    
 0.882
RAPGEF4
Rap guanine nucleotide exchange factor 4.
    
 0.838
ENSJHYP00000008445
annotation not available
  
 0.818
MET
MET proto-oncogene, receptor tyrosine kinase.
  
 0.818
SHANK3
SH3 and multiple ankyrin repeat domains 3.
  
 0.788
BRAF
B-Raf proto-oncogene, serine/threonine kinase.
  
 0.782
RAF1
Raf-1 proto-oncogene, serine/threonine kinase.
  
 0.782
NF1
Neurofibromin 1.
    
 0.775
Your Current Organism:
Junco hyemalis
NCBI taxonomy Id: 40217
Other names: J. hyemalis, dark-eyed junco
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.