TFEB protein (Junco hyemalis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

TFEB

Transcription factor EB. (353 aa)

Predicted Functional Partners:

MTOR

0.935

YWHAB

0.920

RPTOR

0.902

MITF

0.871

RRAGB

0.807

YWHAZ

0.709

SFN

0.709

YWHAQ

0.709

YWHAH

0.701

YWHAG

0.701

Your Current Organism:

Junco hyemalis

NCBI taxonomy Id: 40217
Other names: J. hyemalis, dark-eyed junco

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MITF	MTOR	ENSJHYP00000017934	ENSJHYP00000005565	Melanocyte inducing transcription factor.	Mechanistic target of rapamycin kinase.	0.726
MITF	RPTOR	ENSJHYP00000017934	ENSJHYP00000006369	Melanocyte inducing transcription factor.	Regulatory associated protein of MTOR complex 1.	0.657
MITF	RRAGB	ENSJHYP00000017934	ENSJHYP00000000249	Melanocyte inducing transcription factor.	Ras related GTP binding B.	0.619
MITF	SFN	ENSJHYP00000017934	ENSJHYP00000004532	Melanocyte inducing transcription factor.	Stratifin.	0.719
MITF	TFEB	ENSJHYP00000017934	ENSJHYP00000019616	Melanocyte inducing transcription factor.	Transcription factor EB.	0.871
MITF	YWHAB	ENSJHYP00000017934	ENSJHYP00000003592	Melanocyte inducing transcription factor.	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta.	0.748
MITF	YWHAG	ENSJHYP00000017934	ENSJHYP00000016972	Melanocyte inducing transcription factor.	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma.	0.671
MITF	YWHAH	ENSJHYP00000017934	ENSJHYP00000011726	Melanocyte inducing transcription factor.	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta.	0.671
MITF	YWHAQ	ENSJHYP00000017934	ENSJHYP00000009848	Melanocyte inducing transcription factor.	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta.	0.719
MITF	YWHAZ	ENSJHYP00000017934	ENSJHYP00000004041	Melanocyte inducing transcription factor.	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta.	0.719
MTOR	MITF	ENSJHYP00000005565	ENSJHYP00000017934	Mechanistic target of rapamycin kinase.	Melanocyte inducing transcription factor.	0.726
MTOR	RPTOR	ENSJHYP00000005565	ENSJHYP00000006369	Mechanistic target of rapamycin kinase.	Regulatory associated protein of MTOR complex 1.	0.999
MTOR	RRAGB	ENSJHYP00000005565	ENSJHYP00000000249	Mechanistic target of rapamycin kinase.	Ras related GTP binding B.	0.994
MTOR	SFN	ENSJHYP00000005565	ENSJHYP00000004532	Mechanistic target of rapamycin kinase.	Stratifin.	0.667
MTOR	TFEB	ENSJHYP00000005565	ENSJHYP00000019616	Mechanistic target of rapamycin kinase.	Transcription factor EB.	0.935
MTOR	YWHAB	ENSJHYP00000005565	ENSJHYP00000003592	Mechanistic target of rapamycin kinase.	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta.	0.737
MTOR	YWHAG	ENSJHYP00000005565	ENSJHYP00000016972	Mechanistic target of rapamycin kinase.	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma.	0.667
MTOR	YWHAH	ENSJHYP00000005565	ENSJHYP00000011726	Mechanistic target of rapamycin kinase.	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta.	0.667
MTOR	YWHAQ	ENSJHYP00000005565	ENSJHYP00000009848	Mechanistic target of rapamycin kinase.	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta.	0.667
MTOR	YWHAZ	ENSJHYP00000005565	ENSJHYP00000004041	Mechanistic target of rapamycin kinase.	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta.	0.695