node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SFB96765.1 | SFC72687.1 | SAMN05421848_0066 | SAMN05421848_2478 | Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. | Formiminotetrahydrofolate cyclodeaminase. | 0.548 |
SFB97579.1 | SFB99538.1 | SAMN05421848_0091 | SAMN05421848_0162 | Aminomethyltransferase. | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.957 |
SFB97579.1 | SFC09874.1 | SAMN05421848_0091 | SAMN05421848_0536 | Aminomethyltransferase. | L-proline dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | 0.935 |
SFB97579.1 | SFC72687.1 | SAMN05421848_0091 | SAMN05421848_2478 | Aminomethyltransferase. | Formiminotetrahydrofolate cyclodeaminase. | 0.619 |
SFB97579.1 | SFC73517.1 | SAMN05421848_0091 | SAMN05421848_2527 | Aminomethyltransferase. | L-2,4-diaminobutyrate decarboxylase. | 0.734 |
SFB97579.1 | fmt | SAMN05421848_0091 | SAMN05421848_2333 | Aminomethyltransferase. | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | 0.917 |
SFB97579.1 | folD | SAMN05421848_0091 | SAMN05421848_0244 | Aminomethyltransferase. | Methylenetetrahydrofolate dehydrogenase (NADP+); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.952 |
SFB99538.1 | SFB97579.1 | SAMN05421848_0162 | SAMN05421848_0091 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Aminomethyltransferase. | 0.957 |
SFB99538.1 | SFC46552.1 | SAMN05421848_0162 | SAMN05421848_1483 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | 0.465 |
SFB99538.1 | SFC71690.1 | SAMN05421848_0162 | SAMN05421848_2418 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Sarcosine oxidase subunit alpha; Belongs to the GcvT family. | 0.949 |
SFB99538.1 | SFC72687.1 | SAMN05421848_0162 | SAMN05421848_2478 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Formiminotetrahydrofolate cyclodeaminase. | 0.953 |
SFB99538.1 | fmt | SAMN05421848_0162 | SAMN05421848_2333 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | 0.937 |
SFB99538.1 | folD | SAMN05421848_0162 | SAMN05421848_0244 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Methylenetetrahydrofolate dehydrogenase (NADP+); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.800 |
SFC09874.1 | SFB97579.1 | SAMN05421848_0536 | SAMN05421848_0091 | L-proline dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | Aminomethyltransferase. | 0.935 |
SFC09874.1 | SFC71690.1 | SAMN05421848_0536 | SAMN05421848_2418 | L-proline dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | Sarcosine oxidase subunit alpha; Belongs to the GcvT family. | 0.912 |
SFC09874.1 | SFC72687.1 | SAMN05421848_0536 | SAMN05421848_2478 | L-proline dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | Formiminotetrahydrofolate cyclodeaminase. | 0.511 |
SFC09874.1 | SFC73517.1 | SAMN05421848_0536 | SAMN05421848_2527 | L-proline dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | L-2,4-diaminobutyrate decarboxylase. | 0.908 |
SFC46552.1 | SFB99538.1 | SAMN05421848_1483 | SAMN05421848_0162 | 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.465 |
SFC46552.1 | SFC72687.1 | SAMN05421848_1483 | SAMN05421848_2478 | 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | Formiminotetrahydrofolate cyclodeaminase. | 0.615 |
SFC46552.1 | fmt | SAMN05421848_1483 | SAMN05421848_2333 | 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | 0.671 |