STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SEP83591.1Porphobilinogen synthase; Belongs to the ALAD family. (324 aa)    
Predicted Functional Partners:
hemC
Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
 
 0.999
SEP83555.1
Uroporphyrinogen III methyltransferase / synthase.
 
 0.999
hemL
Glutamate-1-semialdehyde 2,1-aminomutase.
 
 
 0.999
SES31264.1
uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase.
 
 
 0.992
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
  
 0.970
SEQ11513.1
uroporphyrinogen-III synthase.
  
 0.948
SER01649.1
Acyl transferase domain-containing protein.
 
 
 0.943
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
 
 
 0.872
SEQ65352.1
Amino acid adenylation domain-containing protein; Belongs to the ATP-dependent AMP-binding enzyme family.
    
  0.871
SEQ79908.1
Amino acid adenylation domain-containing protein.
    
  0.871
Your Current Organism:
Lechevalieria xinjiangensis
NCBI taxonomy Id: 402600
Other names: CGMCC 4.3525, DSM 45081, JCM 15473, L. xinjiangensis, Lechevalieria xinjiangensis Wang et al. 2007, strain R24
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