STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SER53287.12-isopropylmalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. (536 aa)    
Predicted Functional Partners:
SES23613.1
Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds.
  
 0.988
leuC
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
 
 
 0.986
leuD
3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily.
 
 
 0.980
SER53031.1
Acetolactate synthase, small subunit.
 
 
 0.966
SES01803.1
Acetyl/propionyl-CoA carboxylase, alpha subunit.
  
 0.965
SEQ66679.1
Branched-chain amino acid aminotransferase.
  
 0.935
SES35009.1
Branched-chain amino acid aminotransferase.
  
 0.935
leuB
3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily.
 
 0.933
SEP79152.1
4-amino-4-deoxychorismate lyase.
  
 0.927
SEP85741.1
2-oxoglutarate ferredoxin oxidoreductase subunit alpha.
  
 
 0.919
Your Current Organism:
Lechevalieria xinjiangensis
NCBI taxonomy Id: 402600
Other names: CGMCC 4.3525, DSM 45081, JCM 15473, L. xinjiangensis, Lechevalieria xinjiangensis Wang et al. 2007, strain R24
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