node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
FP0039 | hemA | FP0039 | FP0044 | Probable ribosomal-protein-amino-adic N-acetyltransferase. | Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.565 |
FP0039 | hemB | FP0039 | FP0035 | Probable ribosomal-protein-amino-adic N-acetyltransferase. | Porphobilinogen synthase; Belongs to the ALAD family. | 0.844 |
FP0039 | hemC | FP0039 | FP0043 | Probable ribosomal-protein-amino-adic N-acetyltransferase. | Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.502 |
FP0039 | hemD | FP0039 | FP0042 | Probable ribosomal-protein-amino-adic N-acetyltransferase. | Uroporphyrinogen-III synthase. | 0.511 |
FP0039 | hemE | FP0039 | FP0041 | Probable ribosomal-protein-amino-adic N-acetyltransferase. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.686 |
FP0039 | hemF | FP0039 | FP0037 | Probable ribosomal-protein-amino-adic N-acetyltransferase. | Coproporphyrinogen oxidase. | 0.807 |
FP0045 | hemA | FP0045 | FP0044 | Probable transcriptional regulator, AraC family. | Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.570 |
FP0045 | hemC | FP0045 | FP0043 | Probable transcriptional regulator, AraC family. | Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.402 |
FP0045 | hemD | FP0045 | FP0042 | Probable transcriptional regulator, AraC family. | Uroporphyrinogen-III synthase. | 0.402 |
FP0045 | hemH | FP0045 | FP0046 | Probable transcriptional regulator, AraC family. | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. | 0.786 |
gltX | hemA | FP2499 | FP0044 | Glutamate--tRNA ligase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. | Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.952 |
hemA | FP0039 | FP0044 | FP0039 | Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | Probable ribosomal-protein-amino-adic N-acetyltransferase. | 0.565 |
hemA | FP0045 | FP0044 | FP0045 | Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | Probable transcriptional regulator, AraC family. | 0.570 |
hemA | gltX | FP0044 | FP2499 | Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | Glutamate--tRNA ligase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. | 0.952 |
hemA | hemB | FP0044 | FP0035 | Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | Porphobilinogen synthase; Belongs to the ALAD family. | 0.908 |
hemA | hemC | FP0044 | FP0043 | Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.989 |
hemA | hemD | FP0044 | FP0042 | Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | Uroporphyrinogen-III synthase. | 0.814 |
hemA | hemE | FP0044 | FP0041 | Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.816 |
hemA | hemF | FP0044 | FP0037 | Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | Coproporphyrinogen oxidase. | 0.609 |
hemA | hemH | FP0044 | FP0046 | Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. | 0.638 |