STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mvaBHydroxymethylglutaryl-CoA lyase. (288 aa)    
Predicted Functional Partners:
FP0183
Enoyl-CoA hydratase/isomerase family protein; Belongs to the enoyl-CoA hydratase/isomerase family.
 
 
 0.935
atoA
3-oxoacid CoA-transferase subunit B family protein AtoA.
  
 
 0.933
atoD
3-oxoacid CoA-transferase subunit A family protein AtoD.
  
 
 0.932
gltA
Citrate (Si)-synthase; Belongs to the citrate synthase family.
  
 
 0.929
FP0770
Probable acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.926
FP1725
Acetyl-CoA C-acyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.926
sucC
Succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
   
 0.921
sucD
Succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
  
 
 0.912
FP1002
Carboxyltransferase.
 
 0.906
bfmBB
Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase.
     
 0.905
Your Current Organism:
Flavobacterium psychrophilum
NCBI taxonomy Id: 402612
Other names: F. psychrophilum JIP02/86, Flavobacterium psychrophilum JIP02/86, Flavobacterium psychrophilum str. JIP02/86, Flavobacterium psychrophilum strain JIP02/86
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