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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Rpic_1908TIGRFAM: cystathionine beta-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; KEGG: rso:RSc1639 cystathionine beta-lyase. (403 aa)    
Predicted Functional Partners:
metE
5- methyltetrahydropteroyltriglutamate/homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.
  
 
 0.977
Rpic_0149
PFAM: homocysteine S-methyltransferase; KEGG: rso:RSc0295 probable 5-methyltetrahydrofolate--homocysteine methyltransferase (methionine synthase, vitamin-B12 dependent isozyme) protein.
  
 
 0.971
Rpic_0147
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
 
 0.947
Rpic_4877
Cystathionine gamma-synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; KEGG: rso:RS02139 hypothetical protein.
 
 
0.945
Rpic_1991
O-acetylhomoserine/O-acetylserine sulfhydrylase; KEGG: rso:RSc1562 O-acetylhomoserine aminocarboxypropyltransferase; TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein.
 
 
0.944
Rpic_2431
PFAM: Rhodanese domain protein; KEGG: rso:RSc2226 probable thiosulfate sulfurtransferase protein.
 
 
 0.944
ahcY
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
  
 0.941
Rpic_0787
TIGRFAM: cysteine synthase; cysteine synthase B; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: rso:RSc0917 cysteine synthase B; Belongs to the cysteine synthase/cystathionine beta- synthase family.
 
 
 0.931
Rpic_1202
PFAM: homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase NAD-binding; KEGG: rso:RSc1327 homoserine dehydrogenase.
  
 
 0.922
Rpic_3658
KEGG: rso:RSc0091 probable 5,10-methylenetetrahydrofolate reductase oxidoreductase protein; TIGRFAM: 5,10-methylenetetrahydrofolate reductase; PFAM: methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.
  
 
 0.907
Your Current Organism:
Ralstonia pickettii 12J
NCBI taxonomy Id: 402626
Other names: R. pickettii 12J, Ralstonia pickettii str. 12J, Ralstonia pickettii strain 12J
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