Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Rpic_1981TIGRFAM: 3-hydroxybutyrate dehydrogenase; PFAM: short-chain dehydrogenase/reductase SDR; KEGG: rso:RSc1572 3-hydroxybutyrate dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (259 aa)    
Predicted Functional Partners:
Rpic_1982
KEGG: dac:Daci_4265 3-oxoacid CoA-transferase, B subunit; TIGRFAM: 3-oxoacid CoA-transferase, B subunit; PFAM: coenzyme A transferase.
 
 0.975
Rpic_1983
KEGG: pol:Bpro_1905 3-oxoacid CoA-transferase, subunit A; TIGRFAM: 3-oxoacid CoA-transferase, A subunit; PFAM: coenzyme A transferase.
 
  
  0.973
Rpic_2061
PFAM: pyruvate carboxyltransferase; KEGG: reh:H16_B2494 hydroxymethylglutaryl-CoA lyase; Belongs to the alpha-IPM synthase/homocitrate synthase family.
  
 
  0.927
Rpic_0114
PFAM: pyruvate carboxyltransferase; KEGG: rso:RSc0261 hydroxymethylglutaryl-CoA lyase.
   
 
  0.917
Rpic_1378
PFAM: pyruvate carboxyltransferase; KEGG: aav:Aave_1652 pyruvate carboxyltransferase.
   
 
  0.917
Rpic_4270
TIGRFAM: 3-hydroxybutyrate dehydrogenase; PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: rso:RS02396 3-hydroxybutyrate dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
  
 
0.916
adc
Acetoacetate decarboxylase; Catalyzes the conversion of acetoacetate to acetone and carbon dioxide; Belongs to the ADC family.
  
  
  0.913
Rpic_4028
KEGG: fal:FRAAL3149 acetyl-CoA:acetoacetyl-CoA transferase, beta subunit; TIGRFAM: 3-oxoacid CoA-transferase, B subunit; PFAM: coenzyme A transferase.
  
 0.907
Rpic_1209
Putative D--3-hydroxybutyrate oligomer hydrolase lipoprotein transmembrane; Participates in the degradation of poly-3-hydroxybutyrate (PHB). It works downstream of poly(3-hydroxybutyrate) depolymerase, hydrolyzing D(-)-3-hydroxybutyrate oligomers of various length (3HB- oligomers) into 3HB-monomers.
     
 0.902
Rpic_0655
TIGRFAM: acetoacetyl-CoA synthase; PFAM: AMP-dependent synthetase and ligase; KEGG: rme:Rmet_2699 acetyl-CoA synthetase.
     
  0.900
Your Current Organism:
Ralstonia pickettii 12J
NCBI taxonomy Id: 402626
Other names: R. pickettii 12J, Ralstonia pickettii str. 12J, Ralstonia pickettii strain 12J
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