Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Rpic_2007PFAM: aldo/keto reductase; KEGG: reu:Reut_A2881 aldo/keto reductase. (277 aa)    
Predicted Functional Partners:
Rpic_2050
PFAM: PrkA serine kinase; PrkA AAA domain protein; KEGG: reh:H16_B0700 serine protein kinase.
   
    0.694
Rpic_4231
HAD-superfamily hydrolase, subfamily IIB; Removes the phosphate from trehalose 6-phosphate to produce free trehalose.
   
   0.636
Rpic_2008
PFAM: NADH:flavin oxidoreductase/NADH oxidase; KEGG: rme:Rmet_4091 NADH:flavin oxidoreductase/NADH oxidase.
  
  
 0.602
Rpic_4531
PFAM: aldo/keto reductase; KEGG: bxe:Bxe_B1154 oxidoreductase.
 
 
0.601
Rpic_4852
PFAM: aldo/keto reductase; KEGG: bvi:Bcep1808_6440 aldo/keto reductase.
 
 
0.572
Rpic_1440
PFAM: Alcohol dehydrogenase zinc-binding domain protein; KEGG: rso:RSc1766 probable NADP-dependent oxidoreductase oxidoreductase protein.
   
 
 0.548
Rpic_2989
TIGRFAM: transketolase; PFAM: Transketolase domain protein; Transketolase central region; KEGG: rso:RSc2750 transketolase; Belongs to the transketolase family.
   
 
 0.501
Rpic_1993
KEGG: rso:RSc1560 putative transmembrane protein.
   
    0.495
tal
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
  
 
 0.493
Rpic_2581
Superoxide dismutase copper/zinc binding; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family.
   
 
 0.467
Your Current Organism:
Ralstonia pickettii 12J
NCBI taxonomy Id: 402626
Other names: R. pickettii 12J, Ralstonia pickettii str. 12J, Ralstonia pickettii strain 12J
Server load: low (36%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.