STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
acsAacetate/CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (660 aa)    
Predicted Functional Partners:
Rpic_1236
KEGG: rme:Rmet_1390 malate synthase; TIGRFAM: malate synthase A; PFAM: malate synthase; Belongs to the malate synthase family.
   
 0.944
Rpic_2146
KEGG: rso:RSc1991 type II citrate synthase; TIGRFAM: citrate synthase I; PFAM: Citrate synthase; Belongs to the citrate synthase family.
  
 0.943
Rpic_3564
TIGRFAM: DNA binding domain protein, excisionase family; PFAM: regulatory protein MerR; Citrate synthase; KEGG: dac:Daci_4908 citrate synthase.
  
 0.943
Rpic_3860
KEGG: rso:RSp0121 methylcitrate synthase; TIGRFAM: 2-methylcitrate synthase/citrate synthase II; PFAM: Citrate synthase; Belongs to the citrate synthase family.
  
 0.943
Rpic_4041
KEGG: rme:Rmet_4144 citrate synthase.
  
 0.943
Rpic_1335
Succinate CoA transferase; KEGG: reu:Reut_A1290 acetyl-CoA hydrolase; TIGRFAM: succinate CoA transferase; PFAM: acetyl-CoA hydrolase/transferase.
  
 0.930
Rpic_1338
PFAM: Aldehyde Dehydrogenase_; KEGG: rso:RSc1456 putative betaine aldehyde dehydrogenase (BADH) oxidoreductase protein; Belongs to the aldehyde dehydrogenase family.
  
 0.927
Rpic_2498
PFAM: Aldehyde Dehydrogenase_; KEGG: rme:Rmet_5128 aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
 0.927
Rpic_2566
PFAM: Aldehyde Dehydrogenase_; KEGG: rso:RSc2350 probable aldehyde dehydrogenase oxidoreductase protein; Belongs to the aldehyde dehydrogenase family.
  
 0.927
Rpic_3975
TIGRFAM: methylmalonate-semialdehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase_; KEGG: rso:RSp0650 probable methylmalonate-semialdehyde dehydrogenase oxidoreductase protein.
  
 0.927
Your Current Organism:
Ralstonia pickettii 12J
NCBI taxonomy Id: 402626
Other names: R. pickettii 12J, Ralstonia pickettii str. 12J, Ralstonia pickettii strain 12J
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