| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Rpic_2133 | Rpic_2140 | Rpic_2133 | Rpic_2140 | TIGRFAM: FolC bifunctional protein; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; KEGG: rso:RSc1979 probable bifunctional protein: folylpolyglutamate synthase and dihydrofolate synthase. | KEGG: rso:RSc1986 probable transmembrane protein. | 0.400 |
| Rpic_2133 | trpA | Rpic_2133 | Rpic_2135 | TIGRFAM: FolC bifunctional protein; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; KEGG: rso:RSc1979 probable bifunctional protein: folylpolyglutamate synthase and dihydrofolate synthase. | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.707 |
| Rpic_2133 | trpB | Rpic_2133 | Rpic_2137 | TIGRFAM: FolC bifunctional protein; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; KEGG: rso:RSc1979 probable bifunctional protein: folylpolyglutamate synthase and dihydrofolate synthase. | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.630 |
| Rpic_2133 | trpF | Rpic_2133 | Rpic_2138 | TIGRFAM: FolC bifunctional protein; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; KEGG: rso:RSc1979 probable bifunctional protein: folylpolyglutamate synthase and dihydrofolate synthase. | PFAM: N-(5'phosphoribosyl)anthranilate isomerase (PRAI); KEGG: rso:RSc1984 N-(5'-phosphoribosyl)anthranilate isomerase; Belongs to the TrpF family. | 0.585 |
| Rpic_2133 | truA | Rpic_2133 | Rpic_2139 | TIGRFAM: FolC bifunctional protein; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; KEGG: rso:RSc1979 probable bifunctional protein: folylpolyglutamate synthase and dihydrofolate synthase. | tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. | 0.784 |
| Rpic_2140 | Rpic_2133 | Rpic_2140 | Rpic_2133 | KEGG: rso:RSc1986 probable transmembrane protein. | TIGRFAM: FolC bifunctional protein; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; KEGG: rso:RSc1979 probable bifunctional protein: folylpolyglutamate synthase and dihydrofolate synthase. | 0.400 |
| Rpic_2140 | trpA | Rpic_2140 | Rpic_2135 | KEGG: rso:RSc1986 probable transmembrane protein. | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.570 |
| Rpic_2140 | trpB | Rpic_2140 | Rpic_2137 | KEGG: rso:RSc1986 probable transmembrane protein. | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.574 |
| Rpic_2140 | trpF | Rpic_2140 | Rpic_2138 | KEGG: rso:RSc1986 probable transmembrane protein. | PFAM: N-(5'phosphoribosyl)anthranilate isomerase (PRAI); KEGG: rso:RSc1984 N-(5'-phosphoribosyl)anthranilate isomerase; Belongs to the TrpF family. | 0.677 |
| Rpic_2140 | truA | Rpic_2140 | Rpic_2139 | KEGG: rso:RSc1986 probable transmembrane protein. | tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. | 0.910 |
| rplQ | rpoA | Rpic_3270 | Rpic_3271 | PFAM: ribosomal protein L17; KEGG: rso:RSc2992 50S ribosomal protein L17. | DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.995 |
| rplQ | truA | Rpic_3270 | Rpic_2139 | PFAM: ribosomal protein L17; KEGG: rso:RSc2992 50S ribosomal protein L17. | tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. | 0.811 |
| rplQ | truB | Rpic_3270 | Rpic_1119 | PFAM: ribosomal protein L17; KEGG: rso:RSc2992 50S ribosomal protein L17. | tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. | 0.779 |
| rpoA | rplQ | Rpic_3271 | Rpic_3270 | DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | PFAM: ribosomal protein L17; KEGG: rso:RSc2992 50S ribosomal protein L17. | 0.995 |
| rpoA | rsmH | Rpic_3271 | Rpic_3097 | DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | S-adenosyl-methyltransferase MraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. | 0.431 |
| rpoA | truA | Rpic_3271 | Rpic_2139 | DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. | 0.871 |
| rpoA | truB | Rpic_3271 | Rpic_1119 | DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. | 0.812 |
| rsmH | rpoA | Rpic_3097 | Rpic_3271 | S-adenosyl-methyltransferase MraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. | DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.431 |
| rsmH | truA | Rpic_3097 | Rpic_2139 | S-adenosyl-methyltransferase MraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. | tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. | 0.831 |
| tadA | truA | Rpic_1331 | Rpic_2139 | CMP/dCMP deaminase zinc-binding; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. | tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. | 0.744 |