Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
folE2Protein of unknown function DUF198; Converts GTP to 7,8-dihydroneopterin triphosphate. (268 aa)    
Predicted Functional Partners:
ribB
3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.
     
 0.936
Rpic_1330
TIGRFAM: queuosine biosynthesis protein QueD; PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: rso:RSc1450 putative 6-pyruvoyl tetrahydrobiopterin synthase protein.
    
 0.931
Rpic_0343
PFAM: NUDIX hydrolase; KEGG: rso:RSc0468 dATP pyrophosphohydrolase.
  
  
  0.911
Rpic_0798
KEGG: vei:Veis_2978 alkaline phosphatase.
     
  0.900
moaA
Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.
     
  0.900
Rpic_3653
PFAM: Alkaline phosphatase; KEGG: rso:RSc0098 putative alkaline phosphatase signal peptide protein; Belongs to the alkaline phosphatase family.
     
  0.900
Rpic_3654
PFAM: Alkaline phosphatase; KEGG: rso:RSc0097 putative alkaline phosphatase lipoprotein transmembrane; Belongs to the alkaline phosphatase family.
     
  0.900
ndk
Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
     
  0.800
Rpic_1978
(p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
     
  0.800
Rpic_2106
TIGRFAM: anaerobic ribonucleoside-triphosphate reductase; PFAM: ATP-cone domain protein; KEGG: rso:RSp0963 anaerobic ribonucleoside triphosphate reductase.
     
  0.800
Your Current Organism:
Ralstonia pickettii 12J
NCBI taxonomy Id: 402626
Other names: R. pickettii 12J, Ralstonia pickettii str. 12J, Ralstonia pickettii strain 12J
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