node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Rpic_0958 | uvrB | Rpic_0958 | Rpic_0876 | TIGRFAM: single-stranded-DNA-specific exonuclease RecJ; PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; KEGG: rso:RSc1115 probable single-stranded-DNA-specific exonuclease protein. | Excinuclease ABC, B subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] | 0.406 |
Rpic_0958 | xseA | Rpic_0958 | Rpic_2804 | TIGRFAM: single-stranded-DNA-specific exonuclease RecJ; PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; KEGG: rso:RSc1115 probable single-stranded-DNA-specific exonuclease protein. | Exodeoxyribonuclease VII, large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. | 0.603 |
Rpic_0958 | xseB | Rpic_0958 | Rpic_2428 | TIGRFAM: single-stranded-DNA-specific exonuclease RecJ; PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; KEGG: rso:RSc1115 probable single-stranded-DNA-specific exonuclease protein. | Exodeoxyribonuclease VII, small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. | 0.498 |
Rpic_2427 | Rpic_3068 | Rpic_2427 | Rpic_3068 | PFAM: Polyprenyl synthetase; KEGG: rso:RSc2222 probable geranyltranstransferase (farnesyl-diphosphate synthase) protein; Belongs to the FPP/GGPP synthase family. | PFAM: Polyprenyl synthetase; KEGG: rso:RSc2823 probable octaprenyl-diphosphate synthase (octaprenyl pyrophosphate synthase) protein; Belongs to the FPP/GGPP synthase family. | 0.921 |
Rpic_2427 | dxs | Rpic_2427 | Rpic_2426 | PFAM: Polyprenyl synthetase; KEGG: rso:RSc2222 probable geranyltranstransferase (farnesyl-diphosphate synthase) protein; Belongs to the FPP/GGPP synthase family. | Deoxyxylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | 0.881 |
Rpic_2427 | hemC | Rpic_2427 | Rpic_2571 | PFAM: Polyprenyl synthetase; KEGG: rso:RSc2222 probable geranyltranstransferase (farnesyl-diphosphate synthase) protein; Belongs to the FPP/GGPP synthase family. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.482 |
Rpic_2427 | xseA | Rpic_2427 | Rpic_2804 | PFAM: Polyprenyl synthetase; KEGG: rso:RSc2222 probable geranyltranstransferase (farnesyl-diphosphate synthase) protein; Belongs to the FPP/GGPP synthase family. | Exodeoxyribonuclease VII, large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. | 0.677 |
Rpic_2427 | xseB | Rpic_2427 | Rpic_2428 | PFAM: Polyprenyl synthetase; KEGG: rso:RSc2222 probable geranyltranstransferase (farnesyl-diphosphate synthase) protein; Belongs to the FPP/GGPP synthase family. | Exodeoxyribonuclease VII, small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. | 0.903 |
Rpic_3068 | Rpic_2427 | Rpic_3068 | Rpic_2427 | PFAM: Polyprenyl synthetase; KEGG: rso:RSc2823 probable octaprenyl-diphosphate synthase (octaprenyl pyrophosphate synthase) protein; Belongs to the FPP/GGPP synthase family. | PFAM: Polyprenyl synthetase; KEGG: rso:RSc2222 probable geranyltranstransferase (farnesyl-diphosphate synthase) protein; Belongs to the FPP/GGPP synthase family. | 0.921 |
Rpic_3068 | hemC | Rpic_3068 | Rpic_2571 | PFAM: Polyprenyl synthetase; KEGG: rso:RSc2823 probable octaprenyl-diphosphate synthase (octaprenyl pyrophosphate synthase) protein; Belongs to the FPP/GGPP synthase family. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.512 |
Rpic_3068 | xseA | Rpic_3068 | Rpic_2804 | PFAM: Polyprenyl synthetase; KEGG: rso:RSc2823 probable octaprenyl-diphosphate synthase (octaprenyl pyrophosphate synthase) protein; Belongs to the FPP/GGPP synthase family. | Exodeoxyribonuclease VII, large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. | 0.493 |
Rpic_3068 | xseB | Rpic_3068 | Rpic_2428 | PFAM: Polyprenyl synthetase; KEGG: rso:RSc2823 probable octaprenyl-diphosphate synthase (octaprenyl pyrophosphate synthase) protein; Belongs to the FPP/GGPP synthase family. | Exodeoxyribonuclease VII, small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. | 0.566 |
coaD | uvrB | Rpic_0245 | Rpic_0876 | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Excinuclease ABC, B subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] | 0.419 |
coaD | xseB | Rpic_0245 | Rpic_2428 | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Exodeoxyribonuclease VII, small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. | 0.457 |
dxs | Rpic_2427 | Rpic_2426 | Rpic_2427 | Deoxyxylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | PFAM: Polyprenyl synthetase; KEGG: rso:RSc2222 probable geranyltranstransferase (farnesyl-diphosphate synthase) protein; Belongs to the FPP/GGPP synthase family. | 0.881 |
dxs | xseB | Rpic_2426 | Rpic_2428 | Deoxyxylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | Exodeoxyribonuclease VII, small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. | 0.716 |
fliA | xseB | Rpic_4070 | Rpic_2428 | RNA polymerase, sigma 28 subunit, FliA/WhiG; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes; Belongs to the sigma-70 factor family. FliA subfamily. | Exodeoxyribonuclease VII, small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. | 0.586 |
fliA | yajC | Rpic_4070 | Rpic_2958 | RNA polymerase, sigma 28 subunit, FliA/WhiG; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes; Belongs to the sigma-70 factor family. FliA subfamily. | Preprotein translocase, YajC subunit; The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions. | 0.617 |
hemC | Rpic_2427 | Rpic_2571 | Rpic_2427 | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | PFAM: Polyprenyl synthetase; KEGG: rso:RSc2222 probable geranyltranstransferase (farnesyl-diphosphate synthase) protein; Belongs to the FPP/GGPP synthase family. | 0.482 |
hemC | Rpic_3068 | Rpic_2571 | Rpic_3068 | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | PFAM: Polyprenyl synthetase; KEGG: rso:RSc2823 probable octaprenyl-diphosphate synthase (octaprenyl pyrophosphate synthase) protein; Belongs to the FPP/GGPP synthase family. | 0.512 |