Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Rpic_2575RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70 region 4 type 2; KEGG: rso:RSc2361 probable RNA polymerase sigma-E factor sigma-24 homolog transcription regulator protein; Belongs to the sigma-70 factor family. ECF subfamily. (215 aa)    
Predicted Functional Partners:
Rpic_2576
KEGG: rso:RSc2362 probable transmembrane protein.
 
 
 
 0.926
Rpic_0921
PFAM: Anti sigma-E protein RseA family protein; KEGG: rso:RSc1056 putative transmembrane sigma-E factor negative regulatory transcription regulator protein.
  
 
 0.824
Rpic_4597
RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70 region 4 type 2; KEGG: shl:Shal_3552 RNA polymerase, sigma-24 subunit, ECF subfamily.
  
     0.695
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.678
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.677
Rpic_2574
KEGG: rso:RSc2360 hypothetical protein.
 
    0.637
Rpic_3260
Putative transmembrane anti-sigma factor; KEGG: rso:RSc2982 probable transmembrane protein.
  
 
 0.626
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.624
Rpic_4360
KEGG: bur:Bcep18194_C6587 hypothetical protein.
 
 
 
 0.607
Rpic_3261
RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 4 domain protein; Sigma-70 region 4 type 2; KEGG: rso:RSc2983 probable RNA polymerase sigma-E factor (sigma-24) transcription regulator protein; Belongs to the sigma-70 factor family. ECF subfamily.
  
   
 0.573
Your Current Organism:
Ralstonia pickettii 12J
NCBI taxonomy Id: 402626
Other names: R. pickettii 12J, Ralstonia pickettii str. 12J, Ralstonia pickettii strain 12J
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