node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Rpic_2287 | Rpic_2733 | Rpic_2287 | Rpic_2733 | PFAM: heat shock protein DnaJ domain protein; KEGG: tbd:Tbd_1999 heat shock protein DnaJ. | KEGG: rso:RSc2464 probable ATP-dependent protease (ATP-binding specificity subunit) protein; TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; Belongs to the ClpA/ClpB family. | 0.704 |
Rpic_2287 | Rpic_4935 | Rpic_2287 | Rpic_4935 | PFAM: heat shock protein DnaJ domain protein; KEGG: tbd:Tbd_1999 heat shock protein DnaJ. | PFAM: heat shock protein DnaJ domain protein; KEGG: reh:H16_A1620 DnaJ-class molecular chaperone. | 0.676 |
Rpic_2287 | clpB | Rpic_2287 | Rpic_1210 | PFAM: heat shock protein DnaJ domain protein; KEGG: tbd:Tbd_1999 heat shock protein DnaJ. | ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.704 |
Rpic_2287 | dnaK | Rpic_2287 | Rpic_2870 | PFAM: heat shock protein DnaJ domain protein; KEGG: tbd:Tbd_1999 heat shock protein DnaJ. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.971 |
Rpic_2287 | groL | Rpic_2287 | Rpic_0579 | PFAM: heat shock protein DnaJ domain protein; KEGG: tbd:Tbd_1999 heat shock protein DnaJ. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.677 |
Rpic_2287 | groL-2 | Rpic_2287 | Rpic_3427 | PFAM: heat shock protein DnaJ domain protein; KEGG: tbd:Tbd_1999 heat shock protein DnaJ. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.678 |
Rpic_2287 | groS | Rpic_2287 | Rpic_0578 | PFAM: heat shock protein DnaJ domain protein; KEGG: tbd:Tbd_1999 heat shock protein DnaJ. | Chaperonin Cpn10; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.529 |
Rpic_2287 | grpE | Rpic_2287 | Rpic_2874 | PFAM: heat shock protein DnaJ domain protein; KEGG: tbd:Tbd_1999 heat shock protein DnaJ. | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.933 |
Rpic_2287 | htpG | Rpic_2287 | Rpic_0851 | PFAM: heat shock protein DnaJ domain protein; KEGG: tbd:Tbd_1999 heat shock protein DnaJ. | Heat shock protein Hsp90; Molecular chaperone. Has ATPase activity. | 0.950 |
Rpic_2733 | Rpic_2287 | Rpic_2733 | Rpic_2287 | KEGG: rso:RSc2464 probable ATP-dependent protease (ATP-binding specificity subunit) protein; TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; Belongs to the ClpA/ClpB family. | PFAM: heat shock protein DnaJ domain protein; KEGG: tbd:Tbd_1999 heat shock protein DnaJ. | 0.704 |
Rpic_2733 | Rpic_4935 | Rpic_2733 | Rpic_4935 | KEGG: rso:RSc2464 probable ATP-dependent protease (ATP-binding specificity subunit) protein; TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; Belongs to the ClpA/ClpB family. | PFAM: heat shock protein DnaJ domain protein; KEGG: reh:H16_A1620 DnaJ-class molecular chaperone. | 0.742 |
Rpic_2733 | dnaJ | Rpic_2733 | Rpic_2869 | KEGG: rso:RSc2464 probable ATP-dependent protease (ATP-binding specificity subunit) protein; TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; Belongs to the ClpA/ClpB family. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.744 |
Rpic_2733 | dnaK | Rpic_2733 | Rpic_2870 | KEGG: rso:RSc2464 probable ATP-dependent protease (ATP-binding specificity subunit) protein; TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; Belongs to the ClpA/ClpB family. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.906 |
Rpic_2733 | groL | Rpic_2733 | Rpic_0579 | KEGG: rso:RSc2464 probable ATP-dependent protease (ATP-binding specificity subunit) protein; TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; Belongs to the ClpA/ClpB family. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.515 |
Rpic_2733 | groL-2 | Rpic_2733 | Rpic_3427 | KEGG: rso:RSc2464 probable ATP-dependent protease (ATP-binding specificity subunit) protein; TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; Belongs to the ClpA/ClpB family. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.515 |
Rpic_2733 | groS | Rpic_2733 | Rpic_0578 | KEGG: rso:RSc2464 probable ATP-dependent protease (ATP-binding specificity subunit) protein; TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; Belongs to the ClpA/ClpB family. | Chaperonin Cpn10; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.638 |
Rpic_2733 | grpE | Rpic_2733 | Rpic_2874 | KEGG: rso:RSc2464 probable ATP-dependent protease (ATP-binding specificity subunit) protein; TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; Belongs to the ClpA/ClpB family. | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.866 |
Rpic_2733 | htpG | Rpic_2733 | Rpic_0851 | KEGG: rso:RSc2464 probable ATP-dependent protease (ATP-binding specificity subunit) protein; TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; Belongs to the ClpA/ClpB family. | Heat shock protein Hsp90; Molecular chaperone. Has ATPase activity. | 0.774 |
Rpic_4935 | Rpic_2287 | Rpic_4935 | Rpic_2287 | PFAM: heat shock protein DnaJ domain protein; KEGG: reh:H16_A1620 DnaJ-class molecular chaperone. | PFAM: heat shock protein DnaJ domain protein; KEGG: tbd:Tbd_1999 heat shock protein DnaJ. | 0.676 |
Rpic_4935 | Rpic_2733 | Rpic_4935 | Rpic_2733 | PFAM: heat shock protein DnaJ domain protein; KEGG: reh:H16_A1620 DnaJ-class molecular chaperone. | KEGG: rso:RSc2464 probable ATP-dependent protease (ATP-binding specificity subunit) protein; TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; Belongs to the ClpA/ClpB family. | 0.742 |