Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
Rpic_3209Protease Do; KEGG: rso:RSc2932 probable HtrA-like serine protease signal peptide protein; TIGRFAM: protease Do; PFAM: peptidase S1 and S6 chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; Belongs to the peptidase S1C family. (404 aa)    
Predicted Functional Partners:
Rpic_0921
PFAM: Anti sigma-E protein RseA family protein; KEGG: rso:RSc1056 putative transmembrane sigma-E factor negative regulatory transcription regulator protein.
  
 
 0.776
glpK
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.
   
 0.652
Rpic_3208
PFAM: protein of unknown function DUF34; KEGG: rso:RSc2931 hypothetical protein.
  
    0.625
Rpic_0728
PFAM: Ankyrin; KEGG: rso:RSc0781 probable ankyrin repeat harboring signal peptide protein.
  
 0.516
rplY
Ribosomal 5S rRNA E-loop binding protein Ctc/L25/TL5; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
 
 
   0.509
Rpic_1421
PFAM: Ankyrin; KEGG: rso:RSc1788 probable ankyrin repeat harboring signal peptide protein.
  
 0.489
rplI
Ribosomal protein L9; Binds to the 23S rRNA.
 
 
   0.483
rpsQ
Ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
  
 
   0.468
Rpic_1285
Membrane-associated zinc metalloprotease; KEGG: rso:RSc1411 probable transmembrane protein; TIGRFAM: membrane-associated zinc metalloprotease; PFAM: peptidase M50; SMART: PDZ/DHR/GLGF domain protein.
 
  
 0.463
Rpic_1602
KEGG: rme:Rmet_6236 hypothetical protein.
    
 0.456
Your Current Organism:
Ralstonia pickettii 12J
NCBI taxonomy Id: 402626
Other names: R. pickettii 12J, Ralstonia pickettii str. 12J, Ralstonia pickettii strain 12J
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