STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Rpic_3550PFAM: transcriptional coactivator/pterin dehydratase; KEGG: rso:RSc3356 pterin-4-alpha-carbinolamine dehydratase. (101 aa)    
Predicted Functional Partners:
Rpic_3549
Phenylalanine-4-hydroxylase; KEGG: rso:RSc3355 phenylalanine 4-monooxygenase; TIGRFAM: phenylalanine-4-hydroxylase; PFAM: aromatic amino acid hydroxylase.
 
 0.997
hmgA
Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.
 
  
 0.761
Rpic_4300
PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: bxe:Bxe_B2773 4-hydroxyphenylpyruvate dioxygenase (Hpd).
 
  
 0.734
Rpic_3388
KEGG: rso:RSc3103 probable 4-hydroxyphenylpyruvate dioxygenase oxidoreductase protein; TIGRFAM: 4-hydroxyphenylpyruvate dioxygenase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase.
 
  
 0.733
Rpic_4535
Fumarylacetoacetase; KEGG: rso:RS01759 probable fumarylacetoacetase (fumarylacetoacetate hydrolase) protein; TIGRFAM: fumarylacetoacetase; PFAM: fumarylacetoacetate (FAA) hydrolase; Domain of unknown function DUF1969.
 
  
 0.700
Rpic_0875
Aspartate transaminase; PFAM: aminotransferase class I and II; KEGG: rso:RSc1010 aromatic amino acid aminotransferase.
  
  
 0.635
Rpic_4305
4-hydroxyphenylpyruvate dioxygenase; PFAM: Xylose isomerase domain protein TIM barrel; KEGG: reu:Reut_B5035 4-hydroxyphenylpyruvate dioxygenase.
  
  
 0.495
Rpic_3548
PFAM: regulatory protein AsnC/Lrp family; KEGG: rso:RSc3354 probable transcription regulator protein.
     
 0.443
Rpic_0240
TIGRFAM: maleylacetoacetate isomerase; PFAM: Glutathione S-transferase domain; KEGG: rso:RSc0384 probable maleylacetoacetate isomerase (glutathione transferase zeta 1) protein.
  
  
 0.440
Rpic_0103
PFAM: protein of unknown function DUF1446; KEGG: reh:H16_B0988 hypothetical protein.
  
  
 0.438
Your Current Organism:
Ralstonia pickettii 12J
NCBI taxonomy Id: 402626
Other names: R. pickettii 12J, Ralstonia pickettii str. 12J, Ralstonia pickettii strain 12J
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