STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SJAG_01075NAD-dependent protein deacetylase; Belongs to the sirtuin family. Class I subfamily. (377 aa)    
Predicted Functional Partners:
SJAG_04039
Sir2 family histone deacetylase Hst4.
  
 
0.945
SJAG_04186
Sir2 family histone deacetylase Sir2.
  
 
0.943
SJAG_02889
Nicotinamide-nucleotide adenylyltransferase; Belongs to the eukaryotic NMN adenylyltransferase family.
   
 0.916
SJAG_02618
Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family.
    
 0.915
SJAG_03091
NADH pyrophosphatase.
    
 0.901
SJAG_01566
NAD/NADH kinase.
    
 0.895
SJAG_01359
Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
    
 0.888
SJAG_02017
Translation elongation factor EF-1 gamma subunit.
    
  0.841
SJAG_00303
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
   
 0.827
SJAG_02741
Acetyl-coenzyme A synthetase.
    
 0.823
Your Current Organism:
Schizosaccharomyces japonicus
NCBI taxonomy Id: 402676
Other names: S. japonicus yFS275, Schizosaccharomyces japonicus yFS275
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.