STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SJAG_02556DNA repair endonuclease XPF. (861 aa)    
Predicted Functional Partners:
SJAG_02828
DNA repair endonuclease Swi10.
   
 0.999
SJAG_04171
3'-5' exonuclease domain-containing protein.
    
 0.994
SJAG_02334
XP-A family Rhp14.
    
 0.986
SJAG_04816
DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.
    
 0.970
SJAG_03855
Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.
    
 0.966
SJAG_02517
Cytoplasmic asparagine-tRNA ligase Nrs1.
   
 0.957
SJAG_02031
DNA repair nuclease Rad13.
   
 0.944
SJAG_02262
DUF1767 domain-containing protein.
    
 0.942
SJAG_01044
Holliday junction resolvase subunit Mus81.
    
 0.933
SJAG_01134
Cdc48-Npl4-Ufd1 complex component Npl4.
   
 0.913
Your Current Organism:
Schizosaccharomyces japonicus
NCBI taxonomy Id: 402676
Other names: S. japonicus yFS275, Schizosaccharomyces japonicus yFS275
Server load: low (22%) [HD]