STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SJAG_03145Actin Act1. (375 aa)    
Predicted Functional Partners:
SJAG_01268
Actin-like protein Arp3; Belongs to the actin family.
   
0.996
SJAG_01964
Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.
  
 
0.995
SJAG_04887
Tropomyosin.
   
 0.974
SJAG_03025
Actin depolymerizing factor; Belongs to the actin-binding proteins ADF family.
   
 0.966
SJAG_04982
Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.
    
 0.966
SJAG_02075
Actin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks; Belongs to the WD repeat ARPC1 family.
   
 0.947
SJAG_01732
WASp.
    
 0.935
SJAG_04621
Alpha-actinin.
   
 0.933
SJAG_01611
Actin-related protein 8; Probably involved in transcription regulation via its interaction with the INO80 complex, a chromatin remodeling complex. Belongs to the actin family.
    
0.932
SJAG_03088
Fimbrin.
   
 
 0.927
Your Current Organism:
Schizosaccharomyces japonicus
NCBI taxonomy Id: 402676
Other names: S. japonicus yFS275, Schizosaccharomyces japonicus yFS275
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.