STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
get3ATPase get3; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. S [...] (324 aa)    
Predicted Functional Partners:
get1
Protein get1; Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Acts as a membrane receptor for soluble get3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol.
    
 0.996
SJAG_03865
ER membrane insertion protein.
    
 0.991
SJAG_01940
Sad1 interacting factor 1.
    
 0.944
SJAG_00941
Rad23 Rhp23.
   
 0.940
SJAG_01496
SGT2 family TPR repeat protein.
   
 0.907
SJAG_01667
Dual specificity phosphatase Stp1.
    
 0.832
SJAG_00064
Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum.
    
 0.781
SJAG_00615
Ubiquitin-like protein modifier Ned8.
   
 0.775
SJAG_00452
Ubiquitin.
    
 0.774
SJAG_01448
Boi family protein.
    
 0.763
Your Current Organism:
Schizosaccharomyces japonicus
NCBI taxonomy Id: 402676
Other names: S. japonicus yFS275, Schizosaccharomyces japonicus yFS275
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