node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABO34364.1 | ABO35335.1 | MmarC5_0047 | MmarC5_1029 | PFAM: prephenate dehydratase; KEGG: mmp:MMP1528 prephenate dehydratase. | TIGRFAM: chorismate mutase; PFAM: Chorismate mutase; KEGG: mmp:MMP0578 chorismate mutase. | 0.983 |
ABO34364.1 | aroA | MmarC5_0047 | MmarC5_0385 | PFAM: prephenate dehydratase; KEGG: mmp:MMP1528 prephenate dehydratase. | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.851 |
ABO34364.1 | aroB | MmarC5_0047 | MmarC5_1678 | PFAM: prephenate dehydratase; KEGG: mmp:MMP1528 prephenate dehydratase. | 3-dehydroquinate synthase II; Catalyzes the oxidative deamination and cyclization of 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3- dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis; Belongs to the archaeal-type DHQ synthase family. | 0.824 |
ABO34364.1 | aroC | MmarC5_0047 | MmarC5_0260 | PFAM: prephenate dehydratase; KEGG: mmp:MMP1528 prephenate dehydratase. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.809 |
ABO34364.1 | aroD | MmarC5_0047 | MmarC5_0184 | PFAM: prephenate dehydratase; KEGG: mmp:MMP1528 prephenate dehydratase. | 3-dehydroquinate dehydratase; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. Belongs to the type-I 3-dehydroquinase family. | 0.499 |
ABO34364.1 | aroE | MmarC5_0047 | MmarC5_0743 | PFAM: prephenate dehydratase; KEGG: mmp:MMP1528 prephenate dehydratase. | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.667 |
ABO34364.1 | trpD | MmarC5_0047 | MmarC5_0587 | PFAM: prephenate dehydratase; KEGG: mmp:MMP1528 prephenate dehydratase. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.812 |
ABO35335.1 | ABO34364.1 | MmarC5_1029 | MmarC5_0047 | TIGRFAM: chorismate mutase; PFAM: Chorismate mutase; KEGG: mmp:MMP0578 chorismate mutase. | PFAM: prephenate dehydratase; KEGG: mmp:MMP1528 prephenate dehydratase. | 0.983 |
ABO35335.1 | aroA | MmarC5_1029 | MmarC5_0385 | TIGRFAM: chorismate mutase; PFAM: Chorismate mutase; KEGG: mmp:MMP0578 chorismate mutase. | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.935 |
ABO35335.1 | aroB | MmarC5_1029 | MmarC5_1678 | TIGRFAM: chorismate mutase; PFAM: Chorismate mutase; KEGG: mmp:MMP0578 chorismate mutase. | 3-dehydroquinate synthase II; Catalyzes the oxidative deamination and cyclization of 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3- dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis; Belongs to the archaeal-type DHQ synthase family. | 0.811 |
ABO35335.1 | aroC | MmarC5_1029 | MmarC5_0260 | TIGRFAM: chorismate mutase; PFAM: Chorismate mutase; KEGG: mmp:MMP0578 chorismate mutase. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.990 |
ABO35335.1 | aroD | MmarC5_1029 | MmarC5_0184 | TIGRFAM: chorismate mutase; PFAM: Chorismate mutase; KEGG: mmp:MMP0578 chorismate mutase. | 3-dehydroquinate dehydratase; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. Belongs to the type-I 3-dehydroquinase family. | 0.657 |
ABO35335.1 | aroE | MmarC5_1029 | MmarC5_0743 | TIGRFAM: chorismate mutase; PFAM: Chorismate mutase; KEGG: mmp:MMP0578 chorismate mutase. | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.657 |
ABO35335.1 | aroK | MmarC5_1029 | MmarC5_1354 | TIGRFAM: chorismate mutase; PFAM: Chorismate mutase; KEGG: mmp:MMP0578 chorismate mutase. | TIGRFAM: shikimate kinase; PFAM: GHMP kinase; GHMP kinase, C terminal domain protein; KEGG: mmp:MMP0320 shikimate kinase (archaeal). | 0.516 |
ABO35335.1 | trpD | MmarC5_1029 | MmarC5_0587 | TIGRFAM: chorismate mutase; PFAM: Chorismate mutase; KEGG: mmp:MMP0578 chorismate mutase. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.746 |
ABO35678.1 | aroA-2 | MmarC5_1380 | MmarC5_0890 | PFAM: deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase; KEGG: mmp:MMP0293 hypothetical protein. | 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase; Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7- dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids. | 0.922 |
ABO35678.1 | aroB | MmarC5_1380 | MmarC5_1678 | PFAM: deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase; KEGG: mmp:MMP0293 hypothetical protein. | 3-dehydroquinate synthase II; Catalyzes the oxidative deamination and cyclization of 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3- dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis; Belongs to the archaeal-type DHQ synthase family. | 0.893 |
ABO35678.1 | aroC | MmarC5_1380 | MmarC5_0260 | PFAM: deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase; KEGG: mmp:MMP0293 hypothetical protein. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.723 |
ABO35678.1 | aroK | MmarC5_1380 | MmarC5_1354 | PFAM: deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase; KEGG: mmp:MMP0293 hypothetical protein. | TIGRFAM: shikimate kinase; PFAM: GHMP kinase; GHMP kinase, C terminal domain protein; KEGG: mmp:MMP0320 shikimate kinase (archaeal). | 0.702 |
aroA | ABO34364.1 | MmarC5_0385 | MmarC5_0047 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | PFAM: prephenate dehydratase; KEGG: mmp:MMP1528 prephenate dehydratase. | 0.851 |