STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
argDTIGRFAM: acetylornithine and succinylornithine aminotransferase; PFAM: aminotransferase class-III; KEGG: ret:RHE_CH00516 diaminobutyrate--pyruvate aminotransferase protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (446 aa)    
Predicted Functional Partners:
argJ
Arginine biosynthesis bifunctional protein ArgJ; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family.
 
 
 0.997
argB
Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.
  
 0.995
argC
N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 2 subfamily.
 
 
 0.995
argF
Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
  
 0.988
argH
TIGRFAM: argininosuccinate lyase; PFAM: fumarate lyase; KEGG: nha:Nham_3477 argininosuccinate lyase.
 
  
 0.962
argG
PFAM: argininosuccinate synthase; KEGG: rde:RD1_0417 argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
 
 
 0.957
dapD
TIGRFAM: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase; KEGG: atc:AGR_C_648 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase; Belongs to the transferase hexapeptide repeat family.
    
 0.930
Plav_0407
TIGRFAM: acetylornithine deacetylase (ArgE); PFAM: peptidase M20; peptidase dimerisation domain protein; KEGG: mag:amb2375 acetylornithine deacetylase/succinyl-diaminopimelate desuccinylase and related deacylase.
  
 
 0.921
dapE
Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily.
  
 
 0.919
Plav_1142
TIGRFAM: ornithine carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; KEGG: mcp:MCAP_0654 ornithine carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily.
  
 0.913
Your Current Organism:
Parvibaculum lavamentivorans
NCBI taxonomy Id: 402881
Other names: P. lavamentivorans DS-1, Parvibaculum lavamentivorans DS-1, Parvibaculum lavamentivorans str. DS-1, Parvibaculum lavamentivorans strain DS-1
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