STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Plav_2374PFAM: isochorismatase hydrolase; KEGG: rle:RL0306 putative isochorismatase family protein. (217 aa)    
Predicted Functional Partners:
Plav_2373
Transcriptional regulator, LysR family; PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: atc:AGR_L_471GM hypothetical protein.
 
   
 0.802
Plav_2383
PFAM: Amidohydrolase 3; KEGG: acb:A1S_1451 hypothetical protein.
 
   
 0.783
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
  
 
 0.583
Plav_2386
KEGG: gsu:GSU0801 hypothetical protein.
 
     0.554
Plav_2375
PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: hne:HNE_2501 putative acetolactate synthase; Belongs to the TPP enzyme family.
 
    0.534
Plav_2823
KEGG: rle:pRL120290 hypothetical protein.
 
 
 0.528
Plav_2376
PFAM: aldehyde dehydrogenase; KEGG: hne:HNE_2500 aldehyde dehydrogenase family protein.
 
  
 0.522
nnrD
Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...]
  
    0.515
Plav_1953
SMART: helix-turn-helix domain protein; KEGG: rru:Rru_A3065 transcriptional regulator, XRE family.
   
    0.491
gpsA
Glycerol-3-phosphate dehydrogenase (NAD(P)(+)); PFAM: NADP oxidoreductase coenzyme F420-dependent; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; 6-phosphogluconate dehydrogenase NAD-binding; 3-hydroxyacyl-CoA dehydrogenase NAD-binding; Ketopantoate reductase ApbA/PanE domain protein; KEGG: mmr:Mmar10_0038 glycerol-3-phosphate dehydrogenase (NAD(P)(+)).
  
 
 0.470
Your Current Organism:
Parvibaculum lavamentivorans
NCBI taxonomy Id: 402881
Other names: P. lavamentivorans DS-1, Parvibaculum lavamentivorans DS-1, Parvibaculum lavamentivorans str. DS-1, Parvibaculum lavamentivorans strain DS-1
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