STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Plav_2894PFAM: NADP oxidoreductase coenzyme F420-dependent; 6-phosphogluconate dehydrogenase NAD-binding; KEGG: rpa:RPA1973 3-hydroxyisobutyrate dehydrogenase. (289 aa)    
Predicted Functional Partners:
Plav_1446
TIGRFAM: methylmalonate-semialdehyde dehydrogenase; PFAM: aldehyde dehydrogenase; KEGG: methylmalonate-semialdehyde dehydrogenase, putative.
 
 0.937
Plav_0465
PFAM: Enoyl-CoA hydratase/isomerase; 3-hydroxyacyl-CoA dehydrogenase domain protein; 3-hydroxyacyl-CoA dehydrogenase NAD-binding; KEGG: enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase / 3-hydroxybutyryl-CoA epimerase; Belongs to the enoyl-CoA hydratase/isomerase family.
  
 
 0.929
Plav_2900
TIGRFAM: 3-hydroxyisobutyrate dehydrogenase; PFAM: 6-phosphogluconate dehydrogenase NAD-binding; KEGG: mag:amb3587 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenase; Belongs to the HIBADH-related family.
  
  
 
0.919
Plav_0166
PFAM: aldehyde dehydrogenase; KEGG: mlo:mlr6969 aldehyde dehydrogenase.
 
 
 0.917
Plav_1859
PFAM: aldehyde dehydrogenase; KEGG: hne:HNE_3109 aldehyde dehydrogenase family protein; Belongs to the aldehyde dehydrogenase family.
 
 
 0.917
Plav_0278
PFAM: aminotransferase class-III; KEGG: rpe:RPE_0915 aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
     
 0.902
Plav_2772
Carbamoyl-phosphate synthase L chain ATP-binding; PFAM: biotin/lipoyl attachment domain-containing protein; ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; RimK domain protein ATP-grasp; KEGG: mlo:mll0871 propionyl-CoA carboxylase alpha chain precursor.
  
 
 0.826
acsA
acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 
 0.814
Plav_2084
PFAM: AMP-dependent synthetase and ligase; KEGG: mlo:mll5286 acetyl-CoA synthetase.
  
 
 0.814
Plav_2771
PFAM: carboxyl transferase; KEGG: mlo:mll0348 propionyl-CoA carboxylase.
  
 
  0.806
Your Current Organism:
Parvibaculum lavamentivorans
NCBI taxonomy Id: 402881
Other names: P. lavamentivorans DS-1, Parvibaculum lavamentivorans DS-1, Parvibaculum lavamentivorans str. DS-1, Parvibaculum lavamentivorans strain DS-1
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