STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
glnDMetal dependent phosphohydrolase; TIGRFAM: protein-P-II uridylyltransferase; PFAM: amino acid-binding ACT domain protein; DNA polymerase beta domain protein region; metal-dependent phosphohydrolase HD sub domain; GlnD PII-uridylyltransferase; KEGG: bmb:BruAb1_0141 [protein-pII] uridylyltransferase, hypothetical. (931 aa)    
Predicted Functional Partners:
Plav_3243
PFAM: nitrogen regulatory protein P-II; KEGG: mes:Meso_1545 nitrogen regulatory protein P-II; Belongs to the P(II) protein family.
 
 
 0.963
glnE
(Glutamate--ammonia-ligase) adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal tra [...]
 
   
 0.810
Plav_3130
Signal transduction histidine kinase, nitrogen specific, NtrB; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; KEGG: rpb:RPB_2883 signal transduction histidine kinase, nitrogen specific, NtrB.
  
 
 
 0.670
Plav_1304
PFAM: nitrogen regulatory protein P-II; KEGG: sme:SMc03806 probable nitrogen regulatory protein PII 2; Belongs to the P(II) protein family.
 
 
 
 0.612
bamA
Surface antigen (D15); Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
 
    0.553
Plav_1356
PFAM: nitrogen regulatory protein P-II; KEGG: bcn:Bcen_2252 nitrogen regulatory protein P-II; Belongs to the P(II) protein family.
 
 
 
 0.552
Plav_1964
PFAM: glutamine amidotransferase class-II; glutamate synthase alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: bra:BRADO6238 glutamate synthase [NADPH] large chain (NADPH-GOGAT).
     
 0.525
Plav_3600
PFAM: Methyltransferase type 11; KEGG: sfu:Sfum_3345 hypothetical protein.
       0.471
Plav_3601
Hypothetical protein.
       0.471
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
     
 0.451
Your Current Organism:
Parvibaculum lavamentivorans
NCBI taxonomy Id: 402881
Other names: P. lavamentivorans DS-1, Parvibaculum lavamentivorans DS-1, Parvibaculum lavamentivorans str. DS-1, Parvibaculum lavamentivorans strain DS-1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.