STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PITC_054420Flavin monooxygenase FMO; Belongs to the FMO family. (478 aa)    
Predicted Functional Partners:
COQ3
Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family.
     
 0.452
COQ6
Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6.
   
 0.449
PITC_046590
HAD-superfamily hydrolase, subfamily IA, variant 3.
   
 0.434
PITC_000580
Uncharacterized protein.
   
 0.434
PITC_080860
AB hydrolase-1 domain-containing protein.
   
 0.434
PITC_099790
Uncharacterized protein.
     
 0.431
PITC_042020
Alpha/beta hydrolase fold-3.
   
 
  0.417
PITC_064170
Alpha/beta hydrolase fold-3.
   
 
  0.417
PITC_000620
Alpha/beta hydrolase fold-3.
   
 
  0.417
PITC_053850
Alpha/beta hydrolase fold-3.
   
 
  0.417
Your Current Organism:
Penicillium italicum
NCBI taxonomy Id: 40296
Other names: CBS 339.48, P. italicum
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