STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PITC_018840WSTF/Acf1/Cbp146. (1031 aa)    
Predicted Functional Partners:
PITC_087180
Peptidase aspartic, catalytic.
    
 0.991
PITC_039900
Histone-fold.
    
 
 0.955
PITC_011290
Helicase, C-terminal.
    
 0.941
PITC_018850
Alpha-1,3-glucosyltransferase; Belongs to the ALG6/ALG8 glucosyltransferase family.
 
      0.896
PITC_079500
Histone H2B; Belongs to the histone H2B family.
    
 0.802
PITC_055190
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 0.794
PITC_091130
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 0.794
PITC_041340
Helicase, C-terminal.
   
 0.778
PITC_007380
DNA polymerase V.
    
 0.753
PITC_000410
Helicase, C-terminal.
    
 0.747
Your Current Organism:
Penicillium italicum
NCBI taxonomy Id: 40296
Other names: CBS 339.48, P. italicum
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.