STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PITC_080540WD_REPEATS_REGION domain-containing protein. (983 aa)    
Predicted Functional Partners:
PITC_066120
Short-chain dehydrogenase/reductase SDR.
  
 
 0.866
PITC_013630
Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2; Belongs to the peptidase C19 family.
    
 0.857
PITC_045180
Ubiquitin supergroup.
    
 0.848
PITC_070110
Thiolase-like, subgroup; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.842
PITC_069830
BZIP domain-containing protein.
    
 0.812
PITC_062130
Ribosomal protein S27a.
    
 0.812
PITC_066700
Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family.
  
 0.811
PITC_041050
Uncharacterized protein.
  
 0.810
PITC_073600
Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily.
   
 0.788
PITC_085320
Uncharacterized protein.
  
 0.782
Your Current Organism:
Penicillium italicum
NCBI taxonomy Id: 40296
Other names: CBS 339.48, P. italicum
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.