STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PITC_019500Nudix hydrolase domain-containing protein. (797 aa)    
Predicted Functional Partners:
PITC_063770
NAD(P)H-hydrate epimerase; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
  
 0.975
PITC_024690
Dcp1-like decapping.
    
 0.975
PITC_034540
Topoisomerase II-associated protein PAT1.
    
 0.974
PITC_079410
Helicase, C-terminal; Belongs to the DEAD box helicase family.
    
 0.957
PITC_078370
YjeF N-terminal domain-containing protein.
  
 0.949
PITC_055280
5'-3' exoribonuclease 1; Multifunctional protein that exhibits several independent functions at different levels of the cellular processes. 5'-3' exonuclease component of the nonsense-mediated mRNA decay (NMD) which is a highly conserved mRNA degradation pathway, an RNA surveillance system whose role is to identify and rid cells of mRNA with premature termination codons and thus prevents accumulation of potentially harmful truncated proteins.
   
 0.946
PITC_016370
Ribonucleoprotein LSM domain, eukaryotic/archaea-type.
    
 0.901
PITC_003070
Uncharacterized protein.
    
 0.879
LSM1
U6 snRNA-associated Sm-like protein LSm1; Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation.
    
 0.879
PITC_025240
Ribonuclease CAF1.
    
 
 0.869
Your Current Organism:
Penicillium italicum
NCBI taxonomy Id: 40296
Other names: CBS 339.48, P. italicum
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