STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PITC_060270Transcription elognation factor Eaf, N-terminal. (406 aa)    
Predicted Functional Partners:
PITC_075180
Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.
   
    0.616
PITC_055620
Phosphoribosylglycinamide synthetase, N-terminal.
    
  0.470
PITC_065360
Uncharacterized protein.
  
     0.460
PITC_055650
Uncharacterized protein.
  
     0.439
PITC_086810
Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
  
     0.433
PITC_060280
Cyclin C/H/T/L; Belongs to the cyclin family.
 
      0.426
PITC_066320
F-box domain-containing protein.
  
     0.421
PITC_000180
Uncharacterized protein.
  
     0.421
PITC_031950
Uncharacterized protein.
  
     0.420
PITC_000920
Uncharacterized protein.
  
     0.418
Your Current Organism:
Penicillium italicum
NCBI taxonomy Id: 40296
Other names: CBS 339.48, P. italicum
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.