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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AJE38809.1Carboxylesterase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the type-B carboxylesterase/lipase family. (529 aa)    
Predicted Functional Partners:
AJE43056.1
3'-5' exonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.914
AJE43213.1
Amidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.905
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
   
 0.897
rpsD
30S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
    
  0.895
rpsK
30S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family.
    
  0.892
AJE40206.1
ATP-dependent helicase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.822
AJE41418.1
ATP-dependent helicase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.822
AJE40522.1
Phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  0.821
rpsQ
30S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
   
  0.785
rpsH
30S ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family.
    
  0.765
Your Current Organism:
Streptomyces nodosus
NCBI taxonomy Id: 40318
Other names: ATCC 14899, ATCC 23942, BCRC 13768, CBS 926.68, CCRC 13768, CCRC:13768, DSM 40109, IFO 12895, ISP 5109, JCM 4297, JCM 4656, KCTC 9035, LMG 19340, LMG:19340, NBRC 12895, NCIMB 12816, NRRL B-2371, NRRL-ISP 5109, RIA 831, S. nodosus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.