Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-occurrence
Co-expression
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[Homology]
Score
AJE38985.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (519 aa)    
Predicted Functional Partners:
amphC
Amphotericin polyketide synthase modules 3 to 8.
  
 0.990
amphA
Amphotericin polyketide synthase loading module.
  
 0.990
amphI
Amphotericin polyketide synthase modules 9 to 14; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.990
AJE43565.1
Methylaspartate mutase E subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.987
amphB
Amphotericin polyketide synthase modules 1 and 2.
  
 0.986
AJE43567.1
Monooxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.971
AJE44355.1
Peptide synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.945
AJE44530.1
Non-ribosomal peptide synthetase; Modules 5 to 8 of assembly line related to skyllamycin NRPS.
  
 
 0.941
AJE44064.1
Contains ketosynthase and ACP domains; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.898
amphK
Amphotericin polyketide synthase module 18 and chain-terminating thioesterase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.897
Your Current Organism:
Streptomyces nodosus
NCBI taxonomy Id: 40318
Other names: ATCC 14899, ATCC 23942, BCRC 13768, CBS 926.68, CCRC 13768, CCRC:13768, DSM 40109, IFO 12895, ISP 5109, JCM 4297, JCM 4656, KCTC 9035, LMG 19340, LMG:19340, NBRC 12895, NCIMB 12816, NRRL B-2371, NRRL-ISP 5109, RIA 831, S. nodosus
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