Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
amphDIIIAmphDIII GDP-mannose 4,6-dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose. (344 aa)    
Predicted Functional Partners:
amphDII
AmphDII mycosamine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DegT/DnrJ/EryC1 family.
 
  
 0.954
AJE39651.1
Mannose-1-phosphate guanyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.935
manC
GDP-mannose pyrophosphorylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.913
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
    
   0.646
AJE43950.1
Phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
   0.646
rplD
50S ribosomal protein L4; Forms part of the polypeptide exit tunnel.
 
      0.620
AJE44541.1
NDP-hexose 4-ketoreductase.
 
 
 0.566
amphI
Amphotericin polyketide synthase modules 9 to 14; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.552
AJE42392.1
Reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.548
AJE39406.1
Thioredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thioredoxin family.
    
   0.532
Your Current Organism:
Streptomyces nodosus
NCBI taxonomy Id: 40318
Other names: ATCC 14899, ATCC 23942, BCRC 13768, CBS 926.68, CCRC 13768, CCRC:13768, DSM 40109, IFO 12895, ISP 5109, JCM 4297, JCM 4656, KCTC 9035, LMG 19340, LMG:19340, NBRC 12895, NCIMB 12816, NRRL B-2371, NRRL-ISP 5109, RIA 831, S. nodosus
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