Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
amphGABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (606 aa)    
Predicted Functional Partners:
amphH
ABC transporter ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
0.897
AJE43565.1
Methylaspartate mutase E subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.669
amphB
Amphotericin polyketide synthase modules 1 and 2.
   
 0.668
AJE42394.1
Molybdopterin biosynthesis-like protein MoeZ; The proteins in this cluster have high sequence similarity to MoeB and are possibly involved in the synthesis of molybdopterin, but there has been no biochemical or physiological characterization. There is also no genetic linkage to other molybdopterin cofactor synthesis proteins. These proteins are similar to a Pseudomonas stutzeri protein which is essential to pyridine-2,6-bis(thiocarboxylic acid) synthesis that possibly activates a substrate by adenylation; Derived by automated computational analysis using gene prediction method: Protein [...]
  
 
 0.568
AJE42470.1
Arginine ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     
0.555
amphI
Amphotericin polyketide synthase modules 9 to 14; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.553
AJE41858.1
Acetoin utilization protein AcuC; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  0.541
amphDIII
AmphDIII GDP-mannose 4,6-dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose.
       0.515
AJE40888.1
Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.452
amphA
Amphotericin polyketide synthase loading module.
   
 
 0.445
Your Current Organism:
Streptomyces nodosus
NCBI taxonomy Id: 40318
Other names: ATCC 14899, ATCC 23942, BCRC 13768, CBS 926.68, CCRC 13768, CCRC:13768, DSM 40109, IFO 12895, ISP 5109, JCM 4297, JCM 4656, KCTC 9035, LMG 19340, LMG:19340, NBRC 12895, NCIMB 12816, NRRL B-2371, NRRL-ISP 5109, RIA 831, S. nodosus
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