AJE39547.1 protein (Streptomyces nodosus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

AJE39547.1

Methyltransferase type 11; Derived by automated computational analysis using gene prediction method: Protein Homology. (220 aa)

Predicted Functional Partners:

bioB

0.772

bioD

0.771

bioA

0.754

AJE39543.1

0.715

AJE39553.1

0.548

Your Current Organism:

Streptomyces nodosus

NCBI taxonomy Id: 40318
Other names: ATCC 14899, ATCC 23942, BCRC 13768, CBS 926.68, CCRC 13768, CCRC:13768, DSM 40109, IFO 12895, ISP 5109, JCM 4297, JCM 4656, KCTC 9035, LMG 19340, LMG:19340, NBRC 12895, NCIMB 12816, NRRL B-2371, NRRL-ISP 5109, RIA 831, S. nodosus

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AJE39543.1	AJE39547.1	SNOD_05525	SNOD_05545	8-amino-7-oxononanoate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Methyltransferase type 11; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.715
AJE39543.1	bioA	SNOD_05525	SNOD_05535	8-amino-7-oxononanoate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.	0.995
AJE39543.1	bioB	SNOD_05525	SNOD_05530	8-amino-7-oxononanoate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.	0.956
AJE39543.1	bioD	SNOD_05525	SNOD_05540	8-amino-7-oxononanoate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.	0.990
AJE39547.1	AJE39543.1	SNOD_05545	SNOD_05525	Methyltransferase type 11; Derived by automated computational analysis using gene prediction method: Protein Homology.	8-amino-7-oxononanoate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.715
AJE39547.1	AJE39553.1	SNOD_05545	SNOD_05590	Methyltransferase type 11; Derived by automated computational analysis using gene prediction method: Protein Homology.	GCN5 family acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.548
AJE39547.1	bioA	SNOD_05545	SNOD_05535	Methyltransferase type 11; Derived by automated computational analysis using gene prediction method: Protein Homology.	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.	0.754
AJE39547.1	bioB	SNOD_05545	SNOD_05530	Methyltransferase type 11; Derived by automated computational analysis using gene prediction method: Protein Homology.	Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.	0.772
AJE39547.1	bioD	SNOD_05545	SNOD_05540	Methyltransferase type 11; Derived by automated computational analysis using gene prediction method: Protein Homology.	Dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.	0.771
AJE39553.1	AJE39547.1	SNOD_05590	SNOD_05545	GCN5 family acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Methyltransferase type 11; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.548
AJE39553.1	bioD	SNOD_05590	SNOD_05540	GCN5 family acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.	0.528
bioA	AJE39543.1	SNOD_05535	SNOD_05525	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.	8-amino-7-oxononanoate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.995
bioA	AJE39547.1	SNOD_05535	SNOD_05545	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.	Methyltransferase type 11; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.754
bioA	bioB	SNOD_05535	SNOD_05530	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.	Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.	0.995
bioA	bioD	SNOD_05535	SNOD_05540	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.	Dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.	0.999
bioB	AJE39543.1	SNOD_05530	SNOD_05525	Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.	8-amino-7-oxononanoate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.956
bioB	AJE39547.1	SNOD_05530	SNOD_05545	Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.	Methyltransferase type 11; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.772
bioB	bioA	SNOD_05530	SNOD_05535	Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.	0.995
bioB	bioD	SNOD_05530	SNOD_05540	Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.	Dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.	0.999
bioD	AJE39543.1	SNOD_05540	SNOD_05525	Dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.	8-amino-7-oxononanoate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.990

page 1 of 2

Server load: low (16%) [HD]

Permalink

Network

Neighborhood

Databases

Fusion

Textmining

Co-occurrence

Experiments

Co-expression

© STRING Consortium 2026

Credits

Access

Info

About