Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AJE39648.1MerR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (251 aa)    
Predicted Functional Partners:
AJE39649.1
Signal peptide protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.906
AJE39647.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.844
AJE40890.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.819
AJE39646.1
MerR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.772
AJE42842.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.683
rpoZ
DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
  
 
   0.682
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.588
AJE40164.1
Preprotein translocase subunit SecG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family.
  
    0.575
rpoC
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
   0.570
dinB
DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
       0.548
Your Current Organism:
Streptomyces nodosus
NCBI taxonomy Id: 40318
Other names: ATCC 14899, ATCC 23942, BCRC 13768, CBS 926.68, CCRC 13768, CCRC:13768, DSM 40109, IFO 12895, ISP 5109, JCM 4297, JCM 4656, KCTC 9035, LMG 19340, LMG:19340, NBRC 12895, NCIMB 12816, NRRL B-2371, NRRL-ISP 5109, RIA 831, S. nodosus
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.